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More accurate test may replace PSA

An experimental blood test detects prostate cancer so accurately that it may supplant prostate-specific antigen (PSA) levels as a screening tool. Researchers at Johns Hopkins University in Baltimore discovered an early prostate cancer antigen (EPCA-2) that functions as a biomarker. In a sample of 330 men, EPCA-2 levels were positive in 94% of those who…
News

Prevention of prostate cancer

Men with no signs of prostate cancer should talk to their provider about taking a 5a-reductase inhibitor (5-ARI) for seven years to ward off the disease.
News

Statins may reduce prostate cancer risk

Statins lower prostate-specific antigen (PSA) levels and appear to reduce the risk of prostate cancer itself, according to data from two trials presented at the American Urological Association meeting in Anaheim, Calif., in May. A team of urologists at Duke University studied 1,214 men (mean age 60 years) prescribed a statin between 1990 and 2006…
News

Statins may reduce prostate cancer risk

Statins lower prostate-specific antigen (PSA) levels and appear to reduce the risk of prostate cancer itself, according to data from two trials presented at the American Urological Association meeting in Anaheim, Calif., in May. A team of urologists at Duke University studied 1,214 men (mean age 60 years) prescribed a statin between 1990 and 2006…
Hospital Medicine

Prostate carcinoma

I. What every physician needs to know. Prostate cancer, an adenocarcinoma, is the second most common cause of cancer deaths among men, as well as the most common solid tumor in men, overall. In the past, serial serum PSAs and DREs were used as screening, but recently these tests have become controversial. Diagnosis is based…
Hospital Medicine

Pelvic/Supra-pubic Pain

Pelvic/Supra-Pubic Pain I. Problem/Condition. Pelvic/supra-pubic pain has a wide and varied differential diagnosis. This differential is driven by the overlying structures (skin) as well as the internal organs that populate the pelvic and supra-pubic areas. It is important to understand the quality of the pain (constant versus colicky, dull versus sharp) and consider the time…
Cardiology

Selection of Patients for Cardiac Transplantation

I. Cardiac Transplantation: What every physician needs to know. Cardiac transplantation is the treatment of choice for selected patients with end-stage heart failure. It is estimated that there are 5,700,000 adults in the United States being treated for heart failure (HF), and 620,000 new cases are diagnosed each year. Registries suggest that between 5% and…
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