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Your search for alzheimer disease returned 221 results

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Vitamin B12 Deficiency

At a Glance Diagnosis of vitamin B12 (cobalamin) deficiency is relatively straightforward in long-lasting deficiency, which manifests itself with marked anemia, macrocytosis (mean corpuscular volume [MCV] > 100 fL with ovalocytosis, possibly in conjunction with thrombocytopenia and neutropenia > pancytopenia) neutrophil hypersegmentation (at least 5% of neutrophils with 5 lobes or at least 1% with…

An independent widow’s puzzling hallucinations

The elderly woman saw people who would not respond to her, but she had no dementia or psychiatric conditions. Mrs. T was an 87-year-old widow whose sons were worried that she might be suffering from hallucinations. Concerned, too, about their mother’s gradually increasing frailty, they had recently moved her to an apartment building for senior…

Down Syndrome

Are You Confident of the Diagnosis? Dr John Langdon Down first described Down syndrome in Britain in 1866. Almost a century later, Jérôme Lejeune in 1959 discovered the role of either a partial or complete third copy of chromosome 21 in this condition. This extra genetic material results from trisomy 21 (most common) chromosomal translocation…
Hospital Infection Control

Animals Visiting Healthcare Facilities

Animals Visiting Healthcare Facilities What are the key concepts related to Animals Visiting Healthcare Facilities?  Animals may be present in healthcare (AHC) for multiple reasons and their presence has increased in acute care hospitals and ambulatory medical settings. According to the Humane Society of the United States, pet ownership is common in the United States with 65%…
Nephrology Hypertension

Medical Management of the Dialysis Patient: Cognitive Function, Depression and Psychosocial Adaptation

Does this dialysis patient have delirium, dementia or depression? Delirium is an acute confusional state characterized by a recent onset of fluctuating awareness, impairment of memory and attention, and disorganized thinking that can be attributable to a medical condition, an intoxication, or medication side effects (Table I). In dialysis patients, delirium may also be caused…
Hospital Medicine

Hypogonadism and Testosterone Treatment

Are You Sure the Patient Has Hypogonadism? Male hypogonadism is a clinical syndrome resulting from inadequate testosterone and/or sperm production from the testis. The presence and severity of the clinical manifestations of hypogonadism depend on the degree, duration, and timing of onset. A careful history, medication review, physical examination, and laboratory evaluation are essential to…

Seborrheic Dermatitis (Seborrheic Dermatitis, Seborrheic Eczema, Dermatitis Seborrhoides, Seborrheic dermatitis unspecified, Seborrheic Capitis, Pityriasis Capitis, Scalp Dandruff, Pityriasis Sicca, Infantile seborrheic dermatitis, Seborrheic Blepharitis)

Are You Confident of the Diagnosis? What you should be alert for in the history Patients with widespread, atypical, severe, erythrodermic, alopecic, scarring, treatment-resistant disease and those with systemic symptoms should be further evaluated for other conditions mimicking seborrheic dermatitis. Characteristic findings on physical examination Seborrheic dermatitis commonly presents with pink to erythematous, superficial patches…
Infectious Diseases

Neurologic Disease in the HIV Patient

OVERVIEW: What every practitioner needs to know Are you sure your HIV patient has neurologic disease? What should you expect to find? Common presentations of neurologic disease in HIV patients Symptomatic presentations by anatomical location Clinical presentation of neurologic disease in HIV patients varies depending on the anatomical location of the problem. Brain (chronic) –…

Hydrocephalus procedures

What the Anesthesiologist Should Know before the Operative Procedure Hydrocephalus is an abnormal enlargement of the cerebral ventricles. Causes of hydrocephalus include impaired elimination of cerebral spinal fluid (CSF), and less commonly, an increased production of CSF. Hydrocephalus may present in any age group with a wide variety of symptoms. Prior to the procedure, the…

Mitochondrial diseases

OVERVIEW: What every practitioner needs to know Are you sure your patient has a Mitochondrial disease? What are the typical findings for this disease? Multiorgan system involvement is the hallmark, although some mitochondrial disorders affect a single organ such as the eye in Leber hereditary optic neuropathy (LHON) (see below). Mitochondrial disorders are clinically heterogeneous.…
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