Level 2: Mid-level evidence The risk of cancer was evaluated as a secondary outcome in a randomized trial of 1,024 healthy, community-dwelling, postmenopausal women older than 55 years in rural Nebraska (Am J Clin Nutr. 2007;85:1586-1591). The subjects were randomly assigned to receive 1,400-1,500 mg of supplemental calcium/day alone, supplemental calcium plus 1,100 IU vitamin…
Level 2: Mid-level evidence The use of computer-aided detection in screening mammograms was evaluated in a study of 222,135 women who had 429,345 screening mammograms at 43 separate facilities (N Engl J Med. 2007;356:1399-1409). The reference standard for breast cancer diagnosis was based on clinical diagnosis made within one year subsequent to screening mammography. During…
Company: Kenwood Therapeutics Pharmacologic class: Estrogen Active ingredient: Estradiol 0.06%; gel; contains alcohol. Continue Reading Indication: Moderate-to-severe vasomotor symptoms associated with menopause. Pharmacology: The addition of exogenous estrogens, such as Elestrin, helps to alleviate the vasomotor symptoms associated with declining estrogen levels. Elestrin contains 0.06% estradiol in a hydroalcoholic gel base. One pump actuation delivers…
With the prospect of vaccines eliminating most cases of cervical cancer, the status of the Pap smear is uncertain. Two gynecologists address the issue. Ever since women began getting Pap tests more than 50 years ago, the number of cervical-cancer deaths has dropped dramatically. Once the leading cause of cancer mortality among women in the…