Sickle Cell Disease

L-Glutamine Oral Therapy Reduces Sickle Cell-Related Pain Better Than Placebo

L-Glutamine Oral Therapy Reduces Sickle Cell-Related Pain Better Than Placebo

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L-Glutamine oral treatment with or without hydroxyurea reduces pain crises better than placebo in individuals with sickle cell disease.

Chronic Pain Leads to Higher Opioid Doses and Lower QoL in Sickle Cell Patients

Chronic Pain Leads to Higher Opioid Doses and Lower QoL in Sickle Cell Patients

In adults with sickle cell disease, higher daily opioid use may be associated with poorer health-related quality of life.

Sickle cell trait not linked to increased risk of ischemic stroke

In this meta-analysis of prospective population-based studies, sickle cell trait was not associated with any difference in risk of first ischemic stroke.

Crizanlizumab reduces sickle cell-related pain

Crizanlizumab reduces sickle cell-related pain

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Treatment with high-dose crizanlizumab resulted in an annual rate of sickle cell-related pain crises that was 45.3% lower compared with placebo.

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