Generic Name and Formulations:
Silver sulfadiazine 1%; cream.
Indications for SILVADENE:
Prophylaxis and treatment of sepsis in 2nd and 3rd degree burns.
Apply 1–2 times daily aseptically to approximately 1/16 inch depth to cleansed and debrided burns. Reapply promptly if removed. Continue until wound closed.
Premature infants. Within first 2 months of birth. Late pregnancy.
G6PD deficiency. Impaired renal or hepatic function. Monitor serum sulfa levels and renal function in extensive burns. Avoid eyes. Pregnancy (Cat.B). Nursing mothers: not recommended.
Leukopenia increased with concomitant cimetidine. May inactivate debriding enzymes.
Transient leukopenia, skin necrosis, erythema multiforme, skin discoloration, burning sensation, rash, pruritus, interstitial nephritis, reduction in bacterial growth; systemic sulfonamide reactions, fungal overgrowth.
Crm—20g, 50g, 85g, 400g, 1000g