A 28-year-old man was producing green-colored urine after 2 days in the intensive care unit following a head injury sustained from skate boarding. He was very restless and agitated, needing continuous sedation.
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This patient’s urine was colored green by the propofol he was given for sedation. Although this patient was otherwise asymptomatic, dark green urine can indicate propofol infusion syndrome (PRIS), a serious condition characterized by rhabdomyolysis, hyperlipidemia, acute refractory bradycardia, cardiovascular collapse, severe metabolic acidosis, and hepatomegaly.