Image of the Week: What is causing these ruptured blisters? - Clinical Advisor

Image of the Week: What is causing these ruptured blisters?

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A 60-year-old woman presented with a history of intermittent episodes of tense, fluid-filled blisters covering her abdomen, back, and arms. Upon rupturing, moist erosions developed, resulting in postinflammatory hyperpigmentation as shown in the image above.

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This patient is suspected to have bullous pemphigoid, a relapsing and remitting autoimmune disease in which widespread, tense, fluid-filled cutaneous bullae develop. These may be preceded by a prodromal phase of pruritic skin lesions. Severe pruritus may be the only...

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This patient is suspected to have bullous pemphigoid, a relapsing and remitting autoimmune disease in which widespread, tense, fluid-filled cutaneous bullae develop. These may be preceded by a prodromal phase of pruritic skin lesions. Severe pruritus may be the only manifestation in some patients. It is commonly treated with corticosteroids and immunosuppressants.

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