Image of the Week: Generalized Tonic-Clonic Seizures in an Adolescent - Clinical Advisor

Image of the Week: Generalized Tonic-Clonic Seizures in an Adolescent

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A 16-year-old is brought to the emergency department by his father following a generalized tonic-clonic seizure. The seizures have been occurring since early childhood, although the frequency of episodes has increased over the past 2 months. As an infant, he experienced periods of apnea that resolved at 6 months of age. He has a history of developmental delay and ataxia.

On examination, the patient is mildly disoriented but alert. Mild generalized hypotonia and strabismus are present, and polydactyly is noted bilaterally. Magnetic resonance imaging of the brain is performed, revealing the findings seen here.

Which of the following is this patient most likely to develop?

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