A 16-year-old female presents to her family physician with a 1-year history of skin changes to both palms. She describes these as transient in nature, appearing after she washes her hands, does the dishes, or takes a bath. Examination reveals pitted white papules and marked wrinkling of her palms, 5 minutes after her hands are immersed in water. Which of the following genetic disorders is this patient’s presentation associated with? Learn more about this case, take the quiz, and join the conversation on Figure 1.
The Image of the Week for November 12 is brought to you in partnership with:
Submit your diagnosis to see full explanation.
Learn more about this case, and join the conversation on Figure 1.