Triple Combo Regimens May Address Cause of Cystic Fibrosis
Promising results for VX-659-, VX-445-tezacaftor-ivacaftor for cystic fibrosis with mutations in CFTR.
Diagnosis & Disease Information
Care gaps identified in adolescents as they enter adulthood
The systematic literature review identified risk factors and protective factors that affect adolescents with chronic conditions.
Asthma in adulthood: different and complex
Childhood asthma tends to be allergic, whereas adult forms comprise airway disorders. Our experts tell how to classify, treat, and manage the condition.
Multifaceted approach helps smokers quit
Treating smoking aggressively as a chronic, relapsing disease, can raise the odds for success.
Heart failure strikes young blacks hardest
Young African Americans are developing heart failure (HF) before age 50 years at a rate 20 times higher than whites.
Once-daily hyperuricemia management
Uloric helps prevent uric acid production in patients with gout.
What to do for fatty liver
How would you treat fatty liver in a middle-aged overweight woman with the following profile: liver function tests normal; HDL 70 mg/dL; LDL 160 mg/dL; and triglycerides 170 mg/dL. The patient uses alcohol occasionally, takes no medications, and complains of right upper-quadrant discomfort. One clinician recommends aggressive statin treatment. A second clinician says to treat…
Kidney function affects warfarin action in patients with CKD
Patients with kidney impairment seem to require lower doses of warfarin and may need closer monitoring to avoid serious bleeding complications.
More vitamin C may mean less gout
A large, long-term study links higher vitamin C intake with a lower risk of gout
Aspirin guidelines push stroke prevention
New recommendations call for at-risk men aged 45-79 years to take aspirin daily to prevent a primary heart attack. Similarly, at-risk women aged 55-79 years should take aspirin to prevent a primary ischemic stroke.
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