Prevalence of Alzheimer’s, Related Dementia Set to Double
Alzheimer’s disease and related dementias burden is expected to increase to 3.3% in 2060.
Alzheimer Disease and Dementia
Age, Sex, APOE Genotype Identify Alzheimer’s, Dementia Risk
Three factors help identify absolute 10-year risk of Alzheimer’s disease, all dementia for different groups.
Increased Levels of Human Herpesvirus Identified in Alzheimer’s
Disruption of molecular, genetic, clinical networks by human herpesvirus in brains of subjects with AD.
Cognitive Impairment Profiles Differ Between Parkinson’s, Alzheimer’s
As the neurodegenerative processes of Alzheimer disease and Parkinson disease are different, early cognitive impairment also present differently in these diseases.
New Clinical Guideline for Evaluating Alzheimer’s, Related Dementias
Currently, there are no US consensus on best clinical practice guidelines that incorporate multispecialty recommendations for evaluating cognitive impairment that are thought to be due to Alzheimer’s disease and Related Dementias (ADRD) for use by physicians and nurse practitioners.
Retinal Nerve Fiber Layer Thickness May Be Associated With Cognitive Function
Thinning of the retinal nerve fiber layer has been linked to worsening cognitive function and may be valuable in identifying individuals who may be at risk for cognitive decline.
Diagnosis, Treatments Affected by Amyloid Results in Dementia, Nondementia Patients
In patients with and without dementia, amyloid-positive and negative results were significantly linked to diagnoses and treatment changes.
Genetic Risk Score Better Than APOE Alone for Assessing Risk for Alzheimer’s Dementia
The genetic risk score primarily modified the risk for and onset of dementia and AD among homozygous carriers for APOE ε4.
Dementia, Alzheimer Disease Risk Increased With Lower Branched-Chain Amino Acid Levels
Lower BCAA levels may be associated with an increased risk of incident dementia.
Excessive Daytime Sleepiness Linked to Elevated β-Amyloid Accumulation in Elderly Persons
Elderly individuals without dementia who have elevated daytime sleepiness may be at greater risk for β-amyloid accumulation.
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