Investigators confirmed an association between headache disorders and increased risk for dementia in this pooled meta-analysis; however, the number of studies was small and the population characteristics and study designs were quite heterogenous.
Per study data published in the Journal of Clinical Psychiatry, investigators hypothesized that the correlation between higher Frailty Index scores and increased caregiver burden was partially mediated by increased behavioral and psychological symptoms of dementia.
Poor-quality sleep in later life could be a noninvasive marker for deteriorating brain health.
Authors say frailty should be considered in clinical care, management of Alzheimer dementia.
Findings seen in older adults; independent correlations remained for those with Alzheimer disease.
African-Americans have lower mean CSF concentration of total tau, phosphorylated tau181.
Crude mortality rates for individuals with dementia were 5 times higher than for those without.
Approximately 5.5 million Americans have Alzheimer disease or dementia.
Neurological and neuropsychological examinations were performed to assess intellectual disabilities, and biological assays were performed on collected CSF and plasma.
Findings among individuals with a genetic mutation known to cause Alzheimer’s.
