Autoimmune Disorders

Oral hairy leukoplakia appears as white corrugated lesions on the tongue & is common among severely immunosupressed patients. Secondary infection with Epstein Barr Virus causes OHL. Lesions are usually asymptomatic but may cause altered taste or discomfort, and are sometimes confused with candidiasis. Specific treatment is generally not necessary, as lesions typically resolve with antiretroviral therapy. If the lesions are ulcerated or unusual, clinicians should biopsy to distinguish from cancer

HIV/AIDS-related skin conditions

More than 33.3 million people live with HIV/AIDS worldwide, as of 2009, with 2.6 million people newly infected in that year alone. Although the majority of people affected by HIV/AIDS live in developing nations, more than one million live in the United States and about 21% of those with HIV are unaware of their infection.…

Childhood-onset linear scleroderma on a man’s head. Linear scleroderma is an isolated region of hardened skin. If the bones have been affected, it can stunt the growth of the limbs in children. Photo credit: Dr. Harout Tanielian / Photo Researchers, Inc.


Scleroderma is an autoimmune connective tissue disorder, characterized by a progressive hardening of the skin. The disorder can also affect the blood vessels, muscles and internal organs, including the heart, lungs, kidneys and digestive tract.

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