Women have slightly longer inpatient hospitalizations for bipolar disorder-related symptoms, although factors such as psychotropic treatment and comorbid personality disorders mitigate the results.
Individuals with pediatric-onset bipolar disorder fare better than individuals diagnosed at a later age with the disorder, and bipolar disorder in general is associated with better outcomes than schizophrenia.
Even during full or partial remission, mood instability in bipolar disorder is associated with decreased quality of life and increased stress, according to self-report.
Researchers conducted a literature review of studies on bipolar disorder and bipolar depression to assist NPs in identifying patients with bipolar depression and improving the timeliness of treating the condition.
More frequent manic/mixed and depressive episodes were associated with an increased risk for Parkinson disease.
Given the prevalence of metabolic syndrome and insulin resistance in patients with newly diagnosed bipolar disorder, early intervention may be needed to reduce the risk for cardiovascular disease and premature death.
The FDA has approved the use of Vraylar (cariprazine; Allergan) to treat depressive episodes associated with bipolar I disorder (bipolar depression) in adults.
High frequency of psychiatric admissions for manic/mix, depressive episodes linked to increased risk for PD.
The unaffected siblings of patients with bipolar disorder have increased risks for dyslipidemia and ischemic stroke.
Generalized fractional anisotropy reductions in bundles connecting regions involved in mood regulation and motor function were seen in patients with schizophrenia and bipolar disorder.
