Association Between Proton Pump Inhibitor Use and Mortality Among US Veterans
Researchers sought to investigate the association between proton pump inhibitor use and cause-specific mortality in US Veterans.
Cardiovascular Disease
Liver Disease History Does Not Alter Efficacy and Safety of Edoxaban in AF
A history of mild liver disease is associated with a higher risk for bleeding during anticoagulation therapy but does not change the relative efficacy and safety of edoxaban compared with warfarin in patients with atrial fibrillation.
CVD Risk Up in Later Life for Young Adults With High LDL or Hypertension
Young adult LDL ≥100 mg/dL tied to 64% increased risk for CHD, independent of later levels.
WHO Updates List of Essential Medicines
The World Health Organization (WHO) has updated the WHO Model List of Essential Medicines for 2019.
Nonfasting Lipid Levels Adequate for Assessing Cardiovascular Risk
Fasting, nonfasting levels show similar associations with cardiovascular events even for patients on statins.
Negative Risk Markers for CV Events in Older Adults Identified
Further studies are needed to determine the threshold of risk at which it is safe to withhold therapy for prevention of atherosclerotic cardiovascular disease in elderly people.
Regional Fat With Normal BMI Affects CVD Risk After Menopause
Higher percent trunk fat and lower percent leg fat linked to increased risk of cardiovascular disease.
Direct Oral Anticoagulants Reduce Mortality in Venous Thromboembolism
The safety and efficacy of direct oral anticoagulants were associated with significant overall reductions in mortality in venous thromboembolism compared with observation alone.
Directly Observed Therapy Effective for Treatment-Resistant Hypertension
Regular assessment of adherence to blood pressure-lowering drugs as well as directly observed therapy may be helpful for resolving treatment-resistant hypertension.
Longevity Benefits for Adults Becoming More Physically Active
Lower risk of all-cause mortality for adults with increasing physical activity trajectories over time.
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