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Cardiovascular Disease

Thyrotropin linked to fatal CHD risks in women

Women’s risk of fatal coronary heart disease (CHD) rises with levels of thyrotropin, a hormone that stimulates thyroid function— even when those levels are within the normal range, a recent study suggests…

B vitamins fail to cut CV risk

Evidence continues to mount showing that additional folic acid and B vitamin have no effect on the probability of cardiovascular (CV) events, even among high-risk women…

Creatinine increase after ACE inhibitor

Two readers ask about rising creatinine levels following ACE inhibitor therapy: At what serum creatinine level should discontinuation of an ACE inhibitor or angiotensin receptor blocker be implemented? Is the recommendation different for a patient with diabetes vs. a patient without?—Regina A. Roman, DO, Murrells Inlet, S.C. How long does it take for the creatinine…

Cardiac parameters at odds

When evaluating a patient’s risk of vascular disease, primary-care clinicians often use the cholesterol/HDL ratio, while cardiologists use the LDL level. What should one do if the cholesterol/HDL ratio is favorable, but the LDL is high?—Melvin L. Edwards, MD, Ann Arbor, Mich. The usual reason the ratio is favorable is that the HDL is high.…

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