Naldemedine Therapy May Reduce Symptoms of Opioid-Induced Constipation
Researchers conducted a double-blind study to assess the effect of naldemedine therapy vs placebo in reducing symptoms associated with opioid-induced constipation.
Constipation
DocuSol Kids Available OTC for Children With General Constipation
Each DocuSol Kids mini-enema (5mL) contains a delivered dose of docusate sodium 100mg in a polyethylene glycol base.
Opioid-Induced Constipation: Insights Into Diagnosis and Effective Treatment
Conventional approaches to treatment of opioid-induced constipation include the use of treatment modalities that address non-opioid-related constipation as well as new medications that target the OIC mechanism of action.
AGA: New Opioid-Induced Constipation Management Guidelines Available
The recommendations have been published in the AGA’s official journal, Gastroenterology.
Secretagogues Compared in Irritable Bowel Syndrome With Constipation
While several secretagogues have been recently approved by the Food and Drug Administration (FDA), a lack of head-to-head trials led researchers to conduct a systematic review to compare the effectiveness of these agents in patients with IBS-C.
Constipation: Diagnosis and treatment overview
Strong evidence for efficacy has been established for stimulant and osmotic laxatives, new intestinal secretagogues, and peripherally restricted μ-opiate receptor antagonists, according to a review in JAMA.
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