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Coronary Artery Disease

Addressing cardiac risk in the young

What should I do for patients younger than 40 who have zero to two risk factors for coronary artery disease (CAD) and LDL 130-160 mg/dL if they have not responded to lifestyle modifications?—Derek Olson, DO, Chicago There is no simple answer to this question. It depends what the “risk factors” are. For example, a strong…

What lipid levels lower atheroma burden?

A 70-year-old Asian American man who has signs of hemoconcentration that may be due to plasma contraction also has the following lipid levels: total cholesterol 91 mg/dL, triglycerides 64 mg/dL, LDL 39 mg/dL, HDL 39 mg/dL, and cholesterol-to-HDL ratio 2.3. He takes atorvastatin (Lipitor) and ezetimibe (Zetia) 10 mg each daily. His past history includes…

Fibrate used in combination with statin approved

The FDA has approved Trilipix (fenofibric acid), a delayed-release capsule for use along with diet to treat dyslipidemia. Trilipix is the first fibrate to be approved for use in combination with a statin.

Top 10 health stories of 2008

Blood sugar goals, stem cells, CT scans, health reform–these are some of the issues to make the list of most important stories of the year, as chosen by the Harvard Health Letter.

Statins protect against CVD, not renal disease

Statin use does not decrease renal-function loss in patients without cardiovascular disease (CVD) or in those at risk for it, but the drug is effective for primary prevention of CVD, a study found.

Divergent BPs at Home and the Office

If you record a high BP in the office, but the patient says it is normal at home, should the dosage of his antihypertensive medication be adjusted? Is 24-hour monitoring of…

Trial integrates depression and BP treatment

An integrated approach to hypertension and depression treatment yielded significantly better results for both conditions in a recent six-week pilot study. Patients in the integrated-care arm showed fewer…

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