Diagnosis & Disease Information

Asymptomatic skin lesions

Case #1 A man, aged 38 years, presented with an asymptomatic, colorless, 3-cm lesion on his thigh. The lesion has been present since birth and has remained unchanged in size and appearance. The man was concerned because a friend had recently been diagnosed with amelanotic melanoma. The patient was otherwise in good health with no…

Erythematous scaling lesions

Case #1 A 50-year-old woman with no significant medical history presented with complaints of an enlarging, erythematous eruption. The lesions started three weeks earlier as pink papules on her shoulders, back, and buttocks. Mild pruritus was relieved with diphenhydramine (Benadryl). The woman had also been treating the lesions with an OTC antifungal with no relief.…

Erythematous scaling plaques — some with surrounding hyperpigmentation — in a woman with systemic lupus erythematosus.

Erythematous palmar lesions

CASE #1 A 41-year-old HIV-positive man presents with complaints of a localized eruption on his bilateral palms. The eruption began one week earlier, and there was no associated pruritus or pain. The man had applied petroleum jelly to the lesions without significant improvement. No history of genital ulceration or any other rashes on the body…

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