Diagnosis & Disease Information

Derm Dx: Progressive, tense, bullous lip lesions

A 17-year-old black female presented to the dermatology clinic complaining of acute onset of blisters. The lesions appeared first on her face but were rapidly progressing to other areas of her body. Some rested on erythematous bases, while others had no associated erythema. Most of the lesions were discrete, but some had coalesced into larger…

Derm Dx: A patient with a ‘funny tongue’

A 35-year-old woman presents complaining about the appearance of her tongue. She said she had never really been bothered by the appearance of her tongue until her 8-year-old daughter said, “Mommy, you have a funny tongue.” The patient thinks her tongue has always looked this way. She does not complain of any specific symptoms associate…

Derm Dx: A girl with cardboard-like skin

A 5-year-old girl presents to the pediatric dermatologist for a routine follow-up evaluation. Shortly after birth the patient had developed blisters over her body. Later she developed thickened and ridged scaly skin that resembled corrugated cardboard, predominantly over the flexures and extensors. The patient is otherwise healthy. Her father and the paternal grandmother also had…

Derm Dx: A child with excessive sweating

A 9-year-old female presents complaining that she has experienced excessive sweating of her palms and soles for several years. The patient finds it extremely socially embarrassing and is afraid to shake anyone’s hand. The patient also reports dripping sweat onto her papers at school and occasionally has trouble gripping her pen or pencil because of…

Derm Dx: Red patches on the neck

A 58-year-old man complains that his friends and family have started teasing him that he is a “redneck,” because he has red patches on his neck. He estimates that the problem has developed over the past 15 years. The red patches do not come and go, but remain fixed and are not itchy or painful.…

Derm Dx: Asymptomatic reddish-purple papules

A man in his late 20s presented to the clinic complaining of several reddish-purple papules on his upper thighs and scrotum. He first noticed the bumps several months earlier and asserted that they had not changed in shape, size or color. The bumps were not itchy, painful, or otherwise bothersome, but the patient was concerned…

Derm Dx: An infant with mottled skin

Parents bring their 3-week-old daughter to the dermatology clinic concerned about recurrent mottling of her skin when it’s exposed to cold. The skin changes improve when the skin is warmed, they explain. What’s your diagnosis?

Derm Dx: Bluish nail discoloration

A 66-year-old male presents complaining of a bluish color on his fingernails. He is not significantly bothered by the appearance and is unsure of how long the color has been present, but wants to know the etiology of his nail changes. The patient’s past medical history is significant for diabetes, hyperlipidemia and osteoarthritis. The patient…

Before treatment

Derm Dx: Painful lip swelling, crusting and fissures

A 45-year-old male presents with a six-day history of swelling, crusting and fissuring of the lips. The patient reports significant pain, and says he has been unable to eat. Prior to the eruption the patient reports he applied lip balm for chapped lips. He has no prior history of herpes labialis, and denies being in…

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