Long-Term Antidepressant Use Linked to Weight Gain
The broad use of antidepressants among the general population may be linked to weight gain.
Drug Reactions
Severe Folate Deficiency Associated With Olaparib for Relapsed Ovarian Cancer
In a case study, olaparib was found to induce folate deficiency in most patients with relapsed ovarian cancer. Researchers discuss the significance of this adverse effect and how it was managed.
FDA: Possible Risk of Neural Tube Birth Defects With Certain HIV Meds
The Agency has received reports of serious neural tube birth defects involving the brain, spine, and spinal cord in babies born to women who received dolutegravir for HIV treatment.
Oral Anticoagulation: Reversing the Current View in Bleeding Events
Advances in new reversal agents will be key for managing patients treated with DOACs to prevent major bleeding events.
Antithrombotic drug use linked to higher risk of subdural hematoma
A higher incidence of subdural hematomas is associated with the increased use of antithrombotic drugs, particularly vitamin k antagonists among older patients.
Cannabis health risks and benefits: a report from NASEM
Cannabis health end points include therapeutic effects, cardiometabolic risk, mental health, respiratory disease, and substance abuse.
“Zombie” outbreak in New York City caused by ultrapotent cannabinoid use
The potency of synthetic cannabinoids is consistent with strong depressant effects that account for “zombie-like” behavior.
Grapefruit-drug interactions
Grapefruit can safely be consumed with the majority of medications, and patients with concerns should consult with their physicians.
Exploring the lidocaine with epinephrine myth
Research suggests that injecting lidocaine with epinephrine may not be as dangerous as previously thought.
Statin alternatives in the event of cognitive side effects
How can I best determine if a patient is truly experiencing cognitive side effects of statin medication? If it is decided that he or she must stop taking the statin, what else can I offer for hyperlipidemia that has any evidence of efficacy? — Vikki Stefans, MD, Little Rock, Ark. The best determination of whether a…
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