Hepatitis C therapy interferes with HIV treatment
Taking boceprevir with ritonavir-boosted HIV protease inhibitors together reduces the effectiveness of both therapies, the FDA announced.
Drug Reactions
What causes a metallic taste and burning tongue?
What are the differential diagnoses for a woman aged 60 years with a metallic taste in her mouth and the sensation of a burning tongue?
Is this rash related to terbinafine?
A patient taking terbinafine for onychogryphosis developed a fine pruritic rash over sun exposed body areas while on vacation. Could the drug be to blame?
A spoonful of sugar helps students visualize the metric system
Read this tip for making abstract concepts, like converting metric medication doses, go down smoothly.
Risk for new infections with TNF blockers reported
The FDA is updating boxed warnings on all tumor necrosis factor-alpha inhibiting drugs to reflect risk for infection with the bacteria Legionella and Listeria.
Antipsychotic causes severe allergic reactions
The FDA is warning health care providers about reports of type 1 hypersensitivity reactions among patients taking the antipsychotic asenapine maleate (Saphris), with some cases occurring at first dose.
NSAIDs associated with heart problems
Nonsteroidal anti-inflammatory drugs have been linked with increased risk for atrial fibrillation and adverse events in patients with hypertension and coronary artery disease.
Be vigilant for polypharmacy in cancer patients
An estimated 70% of all U.S. cancer cases diagnosed in 2030 will be among older adults, and the risk of adverse drug reactions and interactions will undoubtedly rise as more elderly patients are prescribed multiple medications.
Arrhythmia risk with high-dose citalopram, FDA warns
The FDA lowered the maximum dose of the antidepressant citalopram hydrobromide (Celexa) from 60 mg per day to 40 mg per day, after concerns that higher doses of the medication increase the risk for cardiac arrhythmia without offering therapeutic benefits.
Antibiotics have no effect on oral contraceptives
While it is true that lower serum ethinyl estradiol and progestin levels have been found in women using combination OCs and antibiotics, these women remain well within the therapeutic window.
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