Extended-Pulsed Fidaxomicin Vs Vancomycin for C difficile Infection
Extended-pulsed fidaxomicin is an efficacious treatment for C difficile infection, regardless of baseline factors.
Gastrointestinal Illnesses
Incidence Trends of Norovirus-Associated Acute Gastroenteritis
Laboratory-confirmed acute gastroenteritis surveillance in the US showed a dynamic prevalence and incidence variability of outpatient and inpatient community-acquired norovirus
Risk Factors for Infant Intussusception After Introduction of Rotavirus Vaccine
The risk of intussusception related to rotavirus vaccination was undetectable as a result of low vaccine coverage and limited statistical power.
Effect of Histo-Blood Group Antigen Status on Enteric Infections in Childhood
Histo-blood group antigens may affect the incidence of all-cause diarrhea and enteric infections in young children.
Early vs Delayed Cholecystectomy in Acute Cholangitis/Acute Cholecystitis
No significant differences in surgical complication risk were seen in early or delayed cholecystectomy for acute cholangitis and acute cholecystitis.
FDA Fast-Tracks Novel Oral Antibiotic for C. difficile Infection
The investigational drug is currently in Phase 1 development, with completion expected in the second quarter of 2019.
GI Illness, Hospitalization Increase, Symptom Reports Decrease Among Older Adults
The number of enteric infection symptom reports was found to decrease with age, although older adults tend to have more severe illness and require hospitalization.
GI Microbiota and Carbapenem-Resistant Pseudomonas aeruginosa Colonization Risk
Decreases in abundance of several taxa may be linked to increased risk for carbapenem-resistant P aeruginosa colonization-acquisition ICU patients.
GI Bleed Hospitalization Risk Linked to Oral Anticoagulant Choice, PPI Cotherapy
To compare the incidence of hospitalization for upper GI tract bleeding, researchers used US Medicare beneficiary files to identify a cohort of patients that were ≥30 years old who initiated oral anticoagulation therapy with apixaban, dabigatran, rivaroxaban, or warfarin, with or without PPI cotherapy.
Low-Dose Imipramine Alternative Treatment for Refractory Functional Dyspepsia
Low-dose imipramine, a tricyclic antidepressant, may benefit patients with functional dyspepsia that is unresponsive to proton pump inhibitors and prokinetic agents.
Next post in Gastroenterology Information Center
