Genes Guide L-Methylfolate Adjuvant Rx for Treatment-Resistant Depression
Genetic testing can be used to identify patients who would benefit from L-methylfolate adjunctive therapy with antidepressants.
Diagnosis & Disease Information
Largest Ever Genome-Wide Association Study Finds Genetic Risk Factors for Anxiety
In an analysis of polygenic risk scores, the researchers identified significant overlap between anxiety and major depressive disorder, as well as PTSD.
Diagnostic Yield of Lynch Syndrome Screening Drops With Age
Incremental diagnostic yield decreases substantially after 70 to 75 years; LS is rare after 80 years.
Cell-Free DNA Testing IDs Trisomy 21 in Twin Pregnancies
Performance of cfDNA test for trisomy 21 in twin pregnancies is similar to that in singleton pregnancies.
Clinicians Should Address Concerns and Limitations of DTC Genetic Testing
Risks related to DTC testing include lack of understanding of the test by the consumer, incorrect test results, and erroneous interpretation of the results.
Gene Therapy Cures Infants Born With SCID-X1
Infants with X-linked severe combined immunodeficiency were found to have fully functioning immune systems following treatment with gene therapy.
Rare Variants Identified in DENND1A Gene in PCOS
Variants are associated with reproductive and metabolic traits in PCOS families.
Gene Therapy Forms New Polysynaptic Pathways in Parkinson
Patients receiving GAD gene therapy develop unique treatment-dependent polysynaptic brain circuit.
Progesterone Receptor Status May Aid Progestin-Based Endometriosis Therapy
Progesterone receptor levels as a biomarker may improve predictability of response to progestin-based therapy for endometriosis.
Independent Links for Genetics, Lifestyle With Incident Stroke
Genetic and lifestyle factors are independently associated with incident stroke among men and women aged 40 to 73 years.
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