1,125,000 Men/Boys Expected to Have Hemophilia Worldwide
Prevalence of all severities of hemophilia A and hemophilia B estimated at 17.1 and 3.8 cases per 100,000.
Hematology
Novel Therapy Treats Triple-Class Refractory Multiple Myeloma
Partial response or better observed in 26% of patients receiving oral selinexor-dexamethasone.
Medicare to Cover CAR-T Therapy for Leukemia, Lymphoma
Chimeric antigen receptor T-cell therapy boosts a patient’s own immune cells.
Depression at Time of Diagnosis May Worsen Survival in Blood Cancers
Risk for death higher even with depression remission vs never experiencing depression.
WHO Updates List of Essential Medicines
The World Health Organization (WHO) has updated the WHO Model List of Essential Medicines for 2019.
Factors Associated With Long-Term Fatigue in Non-Hodgkin Lymphoma Survivors
Severe fatigue was more common in NHL survivors compared with the general population.
Voxelotor Improves Hemoglobin Levels in Sickle Cell Disease
Fewer individuals in voxelotor group versus placebo group have worsened anemia at week 24.
Mortality Not Higher With Transfusions From Female Donors
Findings seen for red blood cells from female, previously pregnant, or sex-discordant donors.
Number of Hematologic Complications of Immune Checkpoint Inhibitors Appears to Be Increasing
Hemolytic anemia and immune thrombocytopenic purpura were the most common complications of immune checkpoint inhibitor therapy.
Body Mass Index Associated With Increased von Willebrand Factor, Factor VIII Levels
For both type 1 and type 2 von Willebrand disease, higher BMI was associated with increased VWF:Ag and FVIII:C levels.
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