OrthoDx: Thoracic Compression Fracture
A 65-year-old man presents with a thoracic compression fracture at T11 that he believes was caused by a fall on his icy driveway. What is the real cause of the compression fracture?
Hematology
Why Are Parents Refusing Vitamin K Administration in Newborns?
Refusal of vitamin K administration is also often correlated with refusal of other preventive care modalities in infants such as hepatitis B vaccination.
Sickle Cell Anemia Update: Gene Therapy Reverses Pain Events for Years
An update on the investigational gene therapy LentiGlobin for sickle cell disease and research on complications and outcomes of this disorder.
Impact of the Opioid Crisis on Pain Treatment in Sickle Cell Disease
Researchers sought to determine what the impact and challenges of the opioid crisis were on pain treatments for patients with sickle cell disease.
Clinical Challenge: Bruising, Bleeding Gums, Nosebleeds in Young College Athlete
A 21-year-old woman presents with complaints of easy bruising, bleeding gums, heavy periods, and nosebleeds. What is her diagnosis?
Major Bleeding Linked to Anticoagulant Overdose in ICU Patients With COVID‑19
Findings from a retrospective chart review showed a need to carefully monitor inflammatory biomarkers and anticoagulant dosage in patients with severe COVID-19.
Model May Predict Postpartum Hemorrhage With Immune Thrombocytopenia
Researchers attempted to develop a predictive model for the risk of postpartum hemorrhage in patients who have ITP.
Quality of Life Improvement Is the Most Important Treatment Goal for Patients With Sickle Cell Disease
Researchers sought to determine what should be the primary treatment goal for patients with sickle cell disease.
CAR-T Cell Therapy Promising in Multiple Myeloma
Researchers sought to determine whether idecabtagene vicleucel, a CAR-T cell therapy, would be a viable treatment option in heavily pretreated patients with relapsed or refractory multiple myeloma.
Falsely Elevated HbA1c in a Patient With Euglycemia
Certain hemoglobin variants and conditions have been shown to affect red blood cell lifespan and hence may lead to false HbA1c results.
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