Herpes Zoster Ophthalmicus Cases Increased in 2004 to 2012
Highest rates of HZO seen in older adults, women, and in whites vs other racial groups.
Herpes Zoster Virus
CDC Examines Safety of Recombinant Zoster Vaccine
Total of 4381 reports of adverse events during first 8 months of use; 3% were serious.
Risk for Zoster Up Before Diagnosis, During Treament of Hematologic Cancer
For solid organ cancers, the risk is greater among those receiving chemotherapy.
Herpes Zoster Recombinant Vaccine Seems Most Effective
However, adjuvant recombinant subunit vaccine tied to more injection site adverse events.
Increased Levels of Human Herpesvirus Identified in Alzheimer’s
Disruption of molecular, genetic, clinical networks by human herpesvirus in brains of subjects with AD.
Vaccination of Auto-HSCT Patients May Reduce the Risk of Herpes Zoster Diagnosis
Early vaccination of autologous hemopoietic stem-cell transplant (auto-HSCT) recipients during the peri-transplant period can be effective for the prevention of infections such as herpes zoster.
Varicella Zoster Vaccine Effective for Hematopoietic Stem Cell Transplant Recipients
In a phase 3 clinical trial, early vaccination effectively prevented herpes zoster in auto-HSCT recipients.
Robust Immune Responses for Herpes Zoster Subunit Vaccine
Humoral response seen for 97.8% of HZ/su vaccine recipients vs 2% of placebo
Herpes zoster subunit vaccine more effective, less expensive than live attenuated herpes zoster vaccine
The adjuvanted herpes zoster subunit vaccine is more effective and less expensive than the live attenuated herpes zoster vaccine at all ages.
CDC committee recommends new shingles vaccine
CDC voted for Shingrix over Zostavax as herpes zoster vaccine of choice
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