Case Study: Retro-orbital Pain and Eyelid Redness
A patient presents to the emergency department complaining of headache behind her left eye and redness of the left eyelid.
Herpes Zoster Virus
Assessing Efficacy, Cost-Effectiveness of Herpes Zoster Vaccination
Researchers sought to compare the effectiveness and cost-savings of the recombinant subunit zoster vaccine with that of the live attenuated zoster vaccine in individuals aged ≥50 years.
Herpes Zoster Ophthalmicus Cases Increased in 2004 to 2012
Highest rates of HZO seen in older adults, women, and in whites vs other racial groups.
CDC Examines Safety of Recombinant Zoster Vaccine
Total of 4381 reports of adverse events during first 8 months of use; 3% were serious.
Risk for Zoster Up Before Diagnosis, During Treament of Hematologic Cancer
For solid organ cancers, the risk is greater among those receiving chemotherapy.
Herpes Zoster Recombinant Vaccine Seems Most Effective
However, adjuvant recombinant subunit vaccine tied to more injection site adverse events.
Increased Levels of Human Herpesvirus Identified in Alzheimer’s
Disruption of molecular, genetic, clinical networks by human herpesvirus in brains of subjects with AD.
Vaccination of Auto-HSCT Patients May Reduce the Risk of Herpes Zoster Diagnosis
Early vaccination of autologous hemopoietic stem-cell transplant (auto-HSCT) recipients during the peri-transplant period can be effective for the prevention of infections such as herpes zoster.
Varicella Zoster Vaccine Effective for Hematopoietic Stem Cell Transplant Recipients
In a phase 3 clinical trial, early vaccination effectively prevented herpes zoster in auto-HSCT recipients.
Robust Immune Responses for Herpes Zoster Subunit Vaccine
Humoral response seen for 97.8% of HZ/su vaccine recipients vs 2% of placebo
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