Further studies will need to look at different subtypes of IBS (IBS-diarrhea, IBS-constipation, IBS-mixed) and improved breath testing, as well as evaluating underlying gut microbiome profiles and how they may affect a response to a low FODMAP diet.
AGA recommends fecal calprotectin, lactoferrin for screening for inflammatory bowel disease.
Mean IBS Symptom Severity Score reduced for telephone-, web-CBT versus treatment as usual
Researchers evaluated the response of rifaximin therapy in patients with IBS-D with abdominal pain symptoms.
Factors have cumulative effect on symptoms as well as on quality of life.
Improvements in symptoms, life impact maintained at 12 months.
In older patients with inflammatory bowel disease, tumor necrosis factor alpha antagonist therapy and vedolizumab were found to be comparable with regard to both safety and effectiveness.
A greater number of early adverse life events as well as more severe traumatic experiences were found to be associated with an increased risk for developing irritable bowel syndrome.
The Company has already completed a Phase 1 trial of this synthetic glucagon-like peptide (GLP-2) analog.
Low vitamin D levels have been linked to multiple diseases including some cancers, neurologic disorders, decrease in bone density, and cognitive decline in the elderly, and research suggests that a possible inflammatory response in the gut when vitamin D levels are low may cause irritable bowel syndrome.
