Apraglutide Gets Orphan Drug Designation for Short Bowel Syndrome
The Company has already completed a Phase 1 trial of this synthetic glucagon-like peptide (GLP-2) analog.
Diagnosis & Disease Information
Irritable Bowel Syndrome and Vitamin D: Is There a Connection?
Low vitamin D levels have been linked to multiple diseases including some cancers, neurologic disorders, decrease in bone density, and cognitive decline in the elderly, and research suggests that a possible inflammatory response in the gut when vitamin D levels are low may cause irritable bowel syndrome.
Loss to Follow-Up Common With IBD
Loss to follow-up is common with inflammatory bowel disease, and both low C-reactive protein levels and long travel time to the hospital are predictors of follow-up loss
Novel Blood Test for Irritable Bowel Syndrome Now Available
The test works by measuring levels of anti-cytolethal distending toxin B (CdtB) and anti-vinculin, 2 biomarkers of post-infectious IBS-D and IBS-M.
Secretagogues Compared in Irritable Bowel Syndrome With Constipation
While several secretagogues have been recently approved by the Food and Drug Administration (FDA), a lack of head-to-head trials led researchers to conduct a systematic review to compare the effectiveness of these agents in patients with IBS-C.
Gut Microbiota Alterations May Not Be Enough to Relieve Irritable Bowel Syndrome
As fecal microbiota transplantation has been found to be effective in treating a number of gastrointestinal diseases, such as Clostridium difficile infection, researchers are now assessing whether it may also be effective for patients with irritable bowel syndrome.
Rifaximin May Improve Abdominal Pain Symptoms in IBS-D
A 2-week course of treatment with rifaximin for diarrhea-predominant irritable bowel syndrome was found to improve abdominal pain symptoms.
FODMAP vs GDA diets for patients with irritable bowel syndrome
Patients with irritable bowel syndrome found FODMAP more beneficial than general dietary advice
Physical and psychological coping skills associated with symptom severity in IBS
The association is partially mediated by levels of anxiety and depressive symptoms.
Inflammatory bowel disease less likely in children and teens from rural areas
Environmental risk factors that predispose people to inflammatory bowel disease may have a stronger effect in children than adults.
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