Hydrocodone Schedule Change Affected Post-Op Opioid Rx
Increase in mean OMEs filled in initial opioid rx after hydrocodone’s change from schedule III to II.
Diagnosis & Disease Information
Testing the Current Guidelines for Antidepressant Treatment of New Onset Depression
Investigators determined that titrating sertraline to 100 mg/day vs 50 mg/day for initial antidepressant therapy for a new MDD episode has no added benefit and increases cost.
Prevalence of Antimicrobial-Contraindicated Drug Combo Prescribing Examined
Researchers performed a cross-sectional study that included multiple year pooled data (2003 to 2011) from the National Ambulatory Medical Care Survey (NAMCS) and the National Hospital Ambulatory Medical Care Survey (NHAMCS Outpatient Department).
Triple Combo Blood Pressure Pill Can Improve BP Control
Proportion achieving target BP increased with use of triple combo pill vs usual care at 6 months.
Daily BCX7353 Cuts Rate of Hereditary Angioedema Attacks
Oral administration of BCX7353 at dose of 125 mg results in lower rate of attacks vs placebo.
Blister Packs for Several Meds Recalled Due to Risk of Harm to Children
The recall affects approximately 470,000 units that include drugs packaged with 3 to 10 tablets per blister card. The blister packs were developed for use in hospitals, however some were sent to retail pharmacies and were likely dispensed for in-home use.
Beta-Blockers Show Varied Effects on Hypoglycemic Mortality Risk in Diabetes
Investigators examined the relationship between the use of β-blockers and incidence of hypoglycemia and risk for mortality in hospitalized patients with diabetes.
AMA: Docs Declare Drug Shortages Public Health Emergency
AMA calls for greater manufacturer transparency in order to prepare for disasters, mitigate shortages.
Post-Op Pain Treatment Gets Breakthrough Therapy Designation
The Company indicated that they will work towards an New Drug Application submission for the treatment in the second half of 2018.
NSAID Use May Increase CVD Risk in Osteoarthritis
Nonsteroidal anti-inflammatory drug use mediated a substantial amount of cardiovascular disease risk in osteoarthritis.
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