New Alzheimer Disease Drug to Be Submitted for FDA Approval
New analysis of study results suggests highest dose of aducanumab may help slow cognitive decline.
Neurocognitive Disorders
Exercise May Slow Brain Deterioration in Alzheimer Disease
Findings did not differ between aerobic exercise and stretching and toning.
Most Diagnosed With Dementia Do Not Receive Specialty Care
Identification of etiological subtype of dementia more likely in patients who see a specialist.
Biopsychosocial Frailty Measure Predicts Risk for Dementia
Model of physical, psychological, and social elements predicts 3- and 7-year dementia risk.
USPSTF: Evidence Lacking for Cognitive Screening in Older Adults
Draft recommendation statement says evidence inadequate for weighing benefits, harms of screening.
Smaller + Larger Infarctions May Escalate Later Cognitive Decline
Cognitive decline associated with only smaller, only larger infarctions did not differ from no infarctions.
More Social Contact at Age 60 Linked to Lower Dementia Risk
More frequent social contact during midlife linked to better subsequent cognitive trajectory.
Family History of Dementia Tied to Early Memory Deficits
Reduced paired-associates learning performance observed long before typical onset of Alzheimer disease.
Cognitive Decline Faster After Incident Coronary Heart Disease Event
Global cognition, verbal memory, temporal orientation scores decline faster after CHD diagnosis.
Higher LDL-C Levels Linked to Early-Onset Alzheimer Disease
Cases with EOAD have higher levels of LDL-C, greater frequency of rare genetic coding variants of APOB.
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