Struggles in Managing Iatrogenic Polypharmacy: Case Study
Even the use of as few as 2 concomitant drugs can introduce the risk for drug interactions and subsequent adverse effects.
Pain
Buprenorphine-Naloxone Found to Be More Cost-Effective Than Extended-Release Naltrexone
Buprenorphine-naloxone may be more cost-effective than extended-release naltrexone as first-line treatment for opioid use disorder.
Meta-Analysis of Opioid Treatment for Chronic Noncancer Pain
Opioids may only provide limited benefits for the management of chronic noncancer pain and may be associated with a greater risk for vomiting.
Pulsed Ultrasound May Be Effective for the Treatment of Rib Fractures
Pulsed ultrasound treatment may represent an effective option for the treatment of stable rib fractures.
One in 5 Back Pain Patients Experience Persistent Pain
Significant differences seen in patterns of medication, health care use across back pain trajectories.
When Opioid Prescribing Guidelines Become Rules
Understanding the current opioid prescribing rules is necessary for clinicians to safely and effectively treat patients with chronic pain conditions.
Greater Walking Frequency, Duration May Reduce Risk for Low Back Pain
Regular and prolonged walking was found to be associated with a reduced the risk for low back pain in Koreans age >50.
Treating Acute Migraine During Pregnancy: The Need for Guidelines
Pregnant women presenting with migraine to acute care settings were found to be treated with therapeutic agents ranging from safe and effective medications to others with unclear efficacy and potential teratogenicity.
Ultrarestrictive Opioid Prescription Protocol May Be Effective for Postoperative Pain Management
Implementation of an ultrarestrictive protocol for opioid prescriptions was found to be associated with reductions in the amount of opioids prescribed after abdominal and gynecologic surgery.
Approved in Migraine, CGRP Antagonists Also Promising in Cluster Headache
Cluster headache and migraine are distinct primary headache disorders that are associated with substantial pain and disability.
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