Researchers conducted an 8-week, open-label, single-arm study and a subsequent 2-stage, sequential, parallel comparison study to assess the use of pimavanserin among patients with Parkinson disease and major depressive disorder.
Researchers sought to determine the relationship between neuroimaging markers and other clinical characteristics with mild parkinsonian signs in older adults.
Severe neuropsychiatric dysfunction, including psychosis and dementia, is associated with more advanced Parkinson disease.
Telephone CBT outperformed treatment-as-usual on all depression, anxiety, quality-of-life measures.
Literature review shows increased likelihood of idiopathic PD with previous diagnosis of BD.
High intensity interval training may increase serum brain-derived neurotrophic factor levels in patients with idiopathic Parkinson disease, along with improvement of neuroplasticity and quality of life.
No association seen between bone mineral density, vitamin D in patients with Parkinson disease.
More frequent manic/mixed and depressive episodes were associated with an increased risk for Parkinson disease.
Advantage of interferon-based antiviral therapy reached statistical significance at 5-year follow-up.
High frequency of psychiatric admissions for manic/mix, depressive episodes linked to increased risk for PD.
