Methotrexate vs tumor necrosis factor inhibitors for pediatric psoriasis
Medication-related adverse events occur more frequently with methotrexate in children with moderate to severe psoriasis.
Psoriasis
Severe psoriasis linked to higher mortality risk
Patients with psoriasis whose disease affects >10% of their body surface area (BSA) are at an increased risk for death compared with the general population.
Sleep disturbance in psoriasis leads to psychological and physical predictors
Sleep complaints among individuals with psoriasis warrant greater clinical attention, as they have a greater chance for developing obstructive sleep apnea.
Psoriasis patients have an increased risk of alcohol-related mortality
Patients with psoriasis have a greater risk of mortality due to alcohol-related causes, including alcoholic liver disease, fibrosis and cirrhosis of the liver, and mental and behavioral disorders.
Secukinumab well-tolerated in patients with scalp psoriasis
This study shows that more than 50% of patients can expect a 90% or greater improvement in scalp psoriasis within 12 weeks.
Smoking may be a risk factor for psoriasis
Researchers observed a positive correlation between the amount and duration of smoking and the occurrence of psoriasis.
Biosimilar ABP 501 and adalimumab safe and effective for plaque psoriasis
Biosimilar ABP 501 has similar clinical efficacy and safety to adalimumab for the treatment of plaque psoriasis.
Dalazatide effective for skin lesions in plaque psoriasis
Dalazatide treatment reduced the plasma levels of multiple inflammation markers and reduced the expression of T cell activation markers on peripheral blood memory T cells.
Screening guidelines for pediatric psoriasis comorbidities
The guidelines are the first to provide recommendations for comorbidity screening in pediatric psoriasis patients.
Cardiometabolic comorbidity rates high in psoriasis patients
The most common comorbidities found in patients with psoriasis are hyperlipidemia, hypertension, depression, type 2 diabetes mellitus, and obesity.
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