Rheumatoid Arthritis Drug Decreases Gut Leakiness, Study Says
Researchers have found that tofacitinib, a drug approved by the FDA to treat rheumatoid arthritis and ulcerative colitis, might also treat leaky gut.
Rheumatoid Arthritis
Few Serious Infections in Offspring Exposed to Non-TNFi Biologics, Tofacitinib
Researchers compared the risk for serious infections in offspring of mothers with chronic inflammatory diseases who received non-TNFi biologics or tofacitinib during pregnancy vs offspring who were unexposed, but exposed to TNFi in utero.
Antibiotic Use Tied to Higher Risk for Rheumatoid Arthritis
Findings show a dose- or frequency-dependent association; all antibiotic classes linked to higher odds for RA.
Cancer Risks Examined in Rheumatoid Arthritis Patients
Increased incidences found for lymphoma, lung cancer (in male patients), and cervical cancer.
Elderly-Onset Rheumatoid Arthritis Ups Bone Erosion Risk
Even 2 years of clinical remission does not protect against bone erosions.
Glucocorticoid Tapering Feasible for Rheumatoid Arthritis Patients
Findings observed in patients achieving low disease activity, remission while receiving tocilizumab.
Disability Often Precedes Rheumatoid Arthritis Diagnosis
Functional disability continues even after diagnosis and treatment.
Breastfeeding Rates Lower Among Women With Rheumatoid Arthritis
Participants indicated that the main reason they discontinued breastfeeding was the restart of their medication.
No Benefit for MRI-Guided Treat-to-Target Strategy in Rheumatoid Arthritis
A treat-to-target strategy guided by magnetic resonance imaging (MRI) did not improve disease activity or reduce radiographic progression compared with a conventional treat-to-target strategy among patients with rheumatoid arthritis (RA) in clinical remission, according to data published in JAMA. Researchers conducted a 2-year, randomized, multicenter trial (ClinicalTrials.gov identifier: NCT01656278) to determine whether an MRI-guided strategy improves outcomes among patients…
Subclinical Myocardial Inflammation Common in Rheumatoid Arthritis
Data show that myocardial inflammation in rheumatoid arthritis is related to disease activity and may contribute to increased risk for heart failure.
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