A clinical decisions support system provides personalized treatment recommendations on lowering cardiovascular risk factors in patients with schizophrenia, schizoaffective disorder, and bipolar disorder.
Three-quarters of all psychiatric disorders occur by early adulthood (mid-20s). This fact suggests that bio-psychosocial factors occurring from the fetal period through early adulthood could play a crucial role in risk. This nonsystematic review sought to synthesize key epidemiological evidence of relevant risk factors.
Researchers investigated the influencing factors, prevalence, and cognitive characteristics of depressive symptoms in older patients with chronic schizophrenia.
Researchers are exploring affective lability as a therapeutic target for bipolar disorder, but limited evidence exists on its prevalence and impact among people with schizophrenia and other psychosis spectrum disorders.
Late-life schizophrenia was associated with disturbances in the antioxidant system, according to findings in BMC Psychiatry.
Incidence of overall mortality was also highest for untreated patients with hepatitis C virus.
With people who have major psychiatric disorders being more likely to have comorbidities which could lead to worse results concerning COVID-19, researchers using a US database assessed the odds of testing positive for COVID-19, as well as mortality from COVID-19.
While extreme phenotype sequencing has brought about the identification of high-impact rare genetic variants for many complex disorders, this has yet to be tested in studies of severe schizophrenia. A total of 112 individuals with severe, extremely treatment resistant schizophrenia were sequenced and the burden of rare, damaging missense and loss-of-function variants between severe, extremely treatment-resistant schizophrenia, typical schizophrenia, and controls across mutation intolerant genes were compared.
In a study, perceptual updating was assessed via a random dot motion perception task. Midway through the test, the motion direction changed. Study participants were then asked to report the direction.
Investigators assessed the relationship between clinical and cognitive features and oddball neural deviations across the schizophrenia-bipolar spectrum.
