Digital Sepsis Monitoring May Improve Inpatient Outcomes
Systemwide implementation presents opportunity to improve care for patients who may have sepsis.
Systemwide implementation presents opportunity to improve care for patients who may have sepsis.
Early infectious diseases consultation is associated with a reduction in in-hospital mortality for patients receiving a severe sepsis and septic shock treatment bundle.
Compared with control states, decrease in sepsis mortality greater after implementation of regulations.
Clovers trial seeks to determine which IV fluids, vasopressors combo works best to curb sepsis.
The use of corticosteroids in sepsis appears to modestly reduce the risk for death and modestly increase neuromuscular weakness but the evidence is not definitive.
Completion of a care bundle for pediatric patients within 1 hour of sepsis recognition, which includes blood cultures, broad-spectrum antibiotics, and a 20-mL/kg intravenous fluid bolus, was associated with lower in-hospital mortality among children with sepsis and septic shock
However, completing individual bundle elements in that timeframe does not reduce pediatric mortality.
Hydrocortisone treatment does not effectively reduce mortality in sepsis.
Patients with septic shock taking phenylephrine during the 2011 norepinephrine shortage experienced higher in-hospital mortality rates.
Approximately 1 in 5 American adults use corticosteroids in the short term, which is associated with an increased risk for sepsis, venous thromboembolism, and fracture.