Sickle Cell Anemia Update: Gene Therapy Reverses Pain Events for Years
An update on the investigational gene therapy LentiGlobin for sickle cell disease and research on complications and outcomes of this disorder.
Sickle Cell Disease
Impact of the Opioid Crisis on Pain Treatment in Sickle Cell Disease
Researchers sought to determine what the impact and challenges of the opioid crisis were on pain treatments for patients with sickle cell disease.
Quality of Life Improvement Is the Most Important Treatment Goal for Patients With Sickle Cell Disease
Researchers sought to determine what should be the primary treatment goal for patients with sickle cell disease.
Transplant Beneficial for Kidney Failure in Sickle Cell
Patients with kidney failure who receive a kidney transplant, including those with sickle cell disease, have lower mortality.
Hematopoietic Stem Cell Transplantation May Not Reduce Renal Function in Sickle Cell Disease
For patients with sickle cell disease, HSCT may not be associated with a significant increase in CKD incidence or prevalence following transplantation.
Endurance Exercise May Offer Vascular Benefit in Sickle Cell Disease
Increases in capillary density, functional exchange surface seen in microvasculature of skeletal muscle.
Voxelotor Improves Hemoglobin Levels in Sickle Cell Disease
Fewer individuals in voxelotor group versus placebo group have worsened anemia at week 24.
Risk Factors for Recurrent Venous Thromboembolism in Patients With Sickle Cell Disease
Patients with severe sickle cell disease were more than twice as likely to experience recurrent thromboembolism compared with patients with less severe disease.
Individualized Management Approach May Improve Care and Cut Costs for Sickle Cell Pain
A multidisciplinary intervention strategy led to a 61% decrease in hospital stay duration for patients with sickle cell disease and vaso-occlusive pain.
Chronic Pain Leads to Higher Opioid Doses and Lower QoL in Sickle Cell Patients
In adults with sickle cell disease, higher daily opioid use may be associated with poorer health-related quality of life.
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