Statin Use Not Linked to Rate of Cognitive Decline in Seniors
Rate of decline in memory, global cognition similar for elderly statin users, never users over 6-year period.
Rate of decline in memory, global cognition similar for elderly statin users, never users over 6-year period.
Inverse link is dose-dependent; lowest 10-year HCC risk seen with 600 or more lipophilic statin cDDDs.
Patients receiving a statin have reduced risk for dementia, independent of cardiovascular meds use.
Significantly faster onset with atorvastatin, rosuvastatin vs simvastatin during monotherapy.
Racial differences persist in statin use among adults, specifically African American adults, who are less likely to be treated with any statin or guideline-recommended statin intensity compared with white adults.
Fifty-six percent of men, 47% of women filled high-intensity statin after myocardial infarction
Statins are associated with an increased risk for developing type 2 diabetes, especially for high-risk individuals.
Compared with nonusers, current statin users experienced markedly decreased risk of CA-SAB.
Stopping statin therapy 3 to 6 months after an initial ischemic stroke may increase risk of a recurrent stroke.
The ALLHAT-LLT trial showed that statin therapy for primary cardiovascular prevention may not benefit adults older than 65 years of age.