Type 2 Diabetes Information Center Archive

News MEDI0382 Safe, Effective for Normalizing Glucose, Weight Loss in Type 2 Diabetes

MEDI0382 Safe, Effective for Normalizing Glucose, Weight Loss in Type 2 Diabetes

MEDI0382 reduced body weight and normalized fasting and postprandial blood glucose levels in patients with type 2 diabetes.

News Chronic Kidney Disease More Common in Type 2 Diabetes Than in Type 1 Diabetes

Chronic Kidney Disease More Common in Type 2 Diabetes Than in Type 1 Diabetes

Investigators examined the prevalence of chronic kidney disease in adults with type 1 diabetes compared with type 2 diabetes.

Healthday Cancer Development Linked to Increased Diabetes Risk

Cancer Development Linked to Increased Diabetes Risk

Increased risk of subsequent diabetes independent of traditional diabetes risk factors

Healthday US Nursing Home Costs Due to Diabetes Vary Greatly by State

US Nursing Home Costs Due to Diabetes Vary Greatly by State

Per-person diabetes-attributable costs ranged from 374 in New Mexico to 1,610 in Washington, D.C.

News Diabetes and Mortality: Comparing SGLT-2 Inhibitors, GLP-1 Agonists, and DPP-4 Inhibitors

Diabetes and Mortality: Comparing SGLT-2 Inhibitors, GLP-1 Agonists, and DPP-4 Inhibitors

For patients with type 2 diabetes, sodium-glucose cotransporter 2 inhibitors and glucagon-like peptide 1 agonists significantly reduce mortality rates compared with dipeptidyl peptidase 4 inhibitors.

News Diabetes Prevalence by Type in the United States: CDC report

Diabetes Prevalence by Type in the United States: CDC report

The CDC conducted a study to estimate the prevalence of diagnosed diabetes among adults in 2016 by primary type.

Feature Case Study in Diabetes: Fungal Infections

Case Study in Diabetes: Fungal Infections

A 68-year-old patient with type 2 diabetes presents to a urologist to evaluate funguria, and a CT scan showed right hydroureteronephrosis.

News Inflammatory Bowel Disease Risk Associated with DPP-4 Inhibitor Use

Inflammatory Bowel Disease Risk Associated with DPP-4 Inhibitor Use

Patients with type 2 diabetes have a greater risk for developing inflammatory bowel disease when using dipeptidyl peptidase-4 inhibitors.

Opinion ACP supports higher HbA1c targets for pharmacotherapy in adults with T2D

ACP supports higher HbA1c targets for pharmacotherapy in adults with T2D

ACP responds to criticism from the ADA, the Endocrine Society, the AACE, and the AADE of guidance that clinicians should aim to achieve an HbA1c level between 7% and 8% in most people with type 2 diabetes.

Video High fiber diet beneficial for gut bacteria development in type 2 diabetes

High fiber diet beneficial for gut bacteria development in type 2 diabetes

A high fiber diet promotes gut bacteria that helps blood glucose control in patients with type 2 diabetes.

News New type 2 diabetes guideline recommends more moderate HbA1c target

New type 2 diabetes guideline recommends more moderate HbA1c target

The American College of Physicians has developed recommendation statements to guide clinicians in selecting targets for pharmacologic treatment of type 2 diabetes.

Healthday Metformin, statins not associated with ovarian cancer

Metformin, statins not associated with ovarian cancer

The incidence of ovarian cancer was not related to metformin or statin usage among women with type 2 diabetes.

News Gestational diabetes increases T2D, hypertension, heart disease risk

Gestational diabetes increases T2D, hypertension, heart disease risk

Women with gestational diabetes have a greater risk of developing T2D and cardiovascular events than women who were not previously diagnosed with the disease.

Video Type 2 diabetes may be reversed with weight loss, physician care

Type 2 diabetes may be reversed with weight loss, physician care

With the help of a doctor and a weight loss plan, new research suggests type 2 diabetes can be reversed in less than a year.

News FDA approves weekly diabetes drug that may also be beneficial for weight loss

FDA approves weekly diabetes drug that may also be beneficial for weight loss

The FDA has approved semaglutide injection as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.

Healthday Commercial weight loss program may help prevent diabetes in obese patients

Commercial weight loss program may help prevent diabetes in obese patients

Primary care referral to Weight Watchers meetings is associated with weight loss, HbA1c reduction.

News Statins associated with increased risk of diabetes in high-risk individuals

Statins associated with increased risk of diabetes in high-risk individuals

Statins are associated with an increased risk for developing type 2 diabetes, especially for high-risk individuals.

News Antidepressant use linked to type 2 diabetes in young adults

Antidepressant use linked to type 2 diabetes in young adults

Type 2 diabetes risk is increased in young adults through antidepressant use, specifically the duration of use and the cumulative dose.

News Cognitive behavioral group therapy ineffective for weight maintenance in type 2 diabetes

Cognitive behavioral group therapy ineffective for weight maintenance in type 2 diabetes

CBGT did not prevent overweight and obese patients with type 2 diabetes from regaining weight lost during weight loss programs.

News Diabetes risk greater in children, young adults on second-generation antipsychotics

Diabetes risk greater in children, young adults on second-generation antipsychotics

Type 2 diabetes is greater with second-generation antipsychotics than with non-second-generation antipsychotic psychotropic medications for patients aged 6 to 25 years.

News Evidence finds link between antidepressant drug use and type 2 diabetes

Evidence finds link between antidepressant drug use and type 2 diabetes

After the inclusion of recent negative studies, a statistically significant association between AD use and diabetes was observed.

News Shorter sleep duration linked to higher diabetes risk in children

Shorter sleep duration linked to higher diabetes risk in children

Sleep duration for 1 hour longer was associated with lower BMI, fat mass, insulin resistance, and fasting glucose but had no effect on HbA1c or cardiovascular risk.

News Lifestyle intervention provides minimal benefit in improving glycemic control in type 2 diabetes

Lifestyle intervention provides minimal benefit in improving glycemic control in type 2 diabetes

Lifestyle interventions maintain glycemic control in patients with type 2 diabetes.

Healthday Earlier menopause may increase risk of type 2 diabetes

Earlier menopause may increase risk of type 2 diabetes

Women who experienced early menopause were 2.4 times more likely to develop diabetes.

News Moderate weight gain in early to middle adulthood linked to increased risk of chronic diseases

Moderate weight gain in early to middle adulthood linked to increased risk of chronic diseases

Adulthood weight gain is associated with an increased risk of major chronic diseases and mortality.

News Type 2 diabetes patients benefit from depression screening

Type 2 diabetes patients benefit from depression screening

The annual screening could decrease negative health outcomes and may be a cost-effective way to reduce complications.

News Degludec vs glargine in type 2 diabetes for cardiovascular events

Degludec vs glargine in type 2 diabetes for cardiovascular events

Degludec is noninferior to glargine regarding the incidence of major cardiovascular events among patients with type 2 diabetes.

News Some antidiabetic agents may increase pneumonia risk in type 2 diabetes

Some antidiabetic agents may increase pneumonia risk in type 2 diabetes

Compared with current use of metformin + sulfonylurea, the use of thiazolidinediones + metformin was associated with an increased risk of community-acquired pneumonia.

News Insulin pump therapy improves quality of life in adolescents with type 2 diabetes

Insulin pump therapy improves quality of life in adolescents with type 2 diabetes

Adolescents with type 2 diabetes decreased HbA1c levels after using insulin pump therapy for a 3-month period.

News High BMI in late adolescence associated with increased risk of severe liver disease in men

High BMI in late adolescence associated with increased risk of severe liver disease in men

A high BMI is associated with an increased risk for severe liver disease, and the risk is higher in those who also have type 2 diabetes mellitus.

News Insulin initiation in primary care improves HbA1c levels

Insulin initiation in primary care improves HbA1c levels

The Stepping Up model of care produced a clinically and significantly significant improvement in HbA1c among adults with type 2 diabetes managed in primary care.

News Nearly half of all cardiometabolic deaths linked to poor diet

Nearly half of all cardiometabolic deaths linked to poor diet

Suboptimal intake of 10 specific dietary factors is associated with a substantial proportion of deaths due to heart disease, stroke, or type 2 diabetes.

Healthday Metformin, vildagliptin have differing effects on heart rate, blood pressure in diabetes

Metformin, vildagliptin have differing effects on heart rate, blood pressure in diabetes

Vildagliptin lowers blood pressure and elevates heart rate, while metformin increases heart rate with no effect on blood pressure.

Opinion Lifestyle modifications vs pharmacologic treatment for patients with diabetes

Lifestyle modifications vs pharmacologic treatment for patients with diabetes

Applying necessary lifestyle changes as well as incorporating pharmaceutical drugs will improve diabetes in patients compared to drugs alone.

Feature Case Study in Diabetes: Use of DPP-4 inhibitors with GLP-1 agonists

Case Study in Diabetes: Use of DPP-4 inhibitors with GLP-1 agonists

A 63-year-old man with type 2 diabetes was admitted to the hospital to undergo right robotic partial nephrectomy.

Healthday Novel oral glucose lowering drugs reduce adverse events in type 2 diabetes

Novel oral glucose lowering drugs reduce adverse events in type 2 diabetes

Researchers observed a reduced risk of all-cause mortality and CVD with dapagliflozin and a lower risk of mortality with dipeptidyl-peptidase-4 inhibitors.

Opinion A differing opinion on the ACP's new diabetes treatment guidelines

A differing opinion on the ACP's new diabetes treatment guidelines

Pharmacotherapy and combination therapy may be a better alternative to the ACP's diabetes treatment guidelines.

News Accuracy of prediabetes screening tests is low

Accuracy of prediabetes screening tests is low

Fasting glucose is specific but not sensitive, and HbA1c is neither sensitive nor specific.

Healthday Mortality risk increased in type 2 diabetes with depression or anxiety

Mortality risk increased in type 2 diabetes with depression or anxiety

Men with diabetes, but not women, had excess mortality risk associated with depression and anxiety.

News Updated guideline for oral pharmacologic treatment of type 2 diabetes

Updated guideline for oral pharmacologic treatment of type 2 diabetes

The ACP has updated the 2012 guideline to provide clinical recommendations of oral pharmacologic treatment of type 2 diabetes.

Healthday Sex hormone-binding globulin and estradiol associated with type 2 diabetes in women

Sex hormone-binding globulin and estradiol associated with type 2 diabetes in women

Women may have a higher risk of type 2 diabetes with low levels of sex hormone-binding globulin and high levels of total estradiol.

News Early intensification of diabetes therapy after metformin failure is beneficial

Early intensification of diabetes therapy after metformin failure is beneficial

Intensification of therapy within 6 months of metformin monotherapy failure resulted in rapid attainment of A1c goals.

News Oily fish consumption may lower diabetic retinopathy risk in type 2 diabetes

Oily fish consumption may lower diabetic retinopathy risk in type 2 diabetes

A target intake of at least 500 mg/d is recommended to combat sight-threatening diabetic retinopathy.

News Drug may slow renal disease progression in type 2 diabetes

Drug may slow renal disease progression in type 2 diabetes

Canagliflozin 100 mg or 300 mg slowed kidney decline compared with glimepiride.

Healthday Adlyxin approved for type 2 diabetes

Adlyxin approved for type 2 diabetes

The once-daily injection works to improve glycemic control.

Feature Cultural considerations in diabetes: controlling HbA1c in a patient observing Ramadan

Cultural considerations in diabetes: controlling HbA1c in a patient observing Ramadan

A patient with type 2 diabetes is undergoing dialysis and needs to control his HbA1c levels while fasting during Ramadan.

News New guidelines support use of metabolic surgery as standard treatment option for type 2 diabetes, obesity

New guidelines support use of metabolic surgery as standard treatment option for type 2 diabetes, obesity

A panel of experts has recommended that metabolic surgery be included as a treatment option for patients with type 2 diabetes and obesity.

News Metformin more effective than sulfonylureas for reducing cardiovascular mortality in diabetes patients

Metformin more effective than sulfonylureas for reducing cardiovascular mortality in diabetes patients

Compared with other drugs for type 2 diabetes, metformin is superior for reducing the risk of cardiovascular mortality.

News FDA issues warning for 2 diabetes drugs linked to risk of heart failure

FDA issues warning for 2 diabetes drugs linked to risk of heart failure

The FDA will add warnings about heart failure risk to the labels of type 2 diabetes medicines containing saxagliptin and alogliptin.

Feature Managing nephropathy in a patient with type 2 diabetes

Managing nephropathy in a patient with type 2 diabetes

A patient with type 2 diabetes presents with elevated microalbumin levels and a recent history of elevated glucose due to bedtime snacking.

News Body fat percentage, physical fitness are better predictors of mortality and diabetes risk than BMI

Body fat percentage, physical fitness are better predictors of mortality and diabetes risk than BMI

High body weight percentage may increase mortality, and poor physical fitness in youth can increase diabetes risk later in life.

Healthday CPAP leads to improved glycemic control in patients with type 2 diabetes

CPAP leads to improved glycemic control in patients with type 2 diabetes

The CPAP group had a larger decrease in HbA1c levels after 6 months.

News Managing diabetes in primary care: 2016 recommendations from ADA

Managing diabetes in primary care: 2016 recommendations from ADA

The ADA has published the 2016 Standards of Medical Care in Diabetes that outline the best practices for diabetes care and management.

News Once-weekly GLP-1RAs beneficial for type 2 diabetes

Once-weekly GLP-1RAs beneficial for type 2 diabetes

Once-weekly GLP-1RAs reduced HbA1c and fasting plasma glucose.

News Is heart failure linked to DPP-4 inhibitor use in patients with diabetes?

Is heart failure linked to DPP-4 inhibitor use in patients with diabetes?

Current evidence is inadequate to determine how DPP-4 inhibitors affect the risk of heart failure in patients with type 2 diabetes.

Healthday Statin plus niacin reduces apoB-48 concentration in type 2 diabetes

Statin plus niacin reduces apoB-48 concentration in type 2 diabetes

A statin plus extended-release niacin reduces apoB-48 concentrations in patients with type 2 diabetes, compared with a statin alone.

Healthday Patients with type 2 diabetes may undergo unnecessary HbA1c testing

Patients with type 2 diabetes may undergo unnecessary HbA1c testing

More than 60% of the 31,545 patients analyzed between 2001 and 2013 underwent HbA1c at least four times per year.

Healthday Breastfeeding may reduce odds of developing type 2 diabetes

Breastfeeding may reduce odds of developing type 2 diabetes

Breastfeeding for 2 or more months may reduce the odds of developing type 2 diabetes in mothers previously diagnosed with gestational diabetes.

Feature Severe insulin resistance in a patient with type 2 diabetes

Severe insulin resistance in a patient with type 2 diabetes

Patients with type 2 diabetes and severe insulin resistance may require large doses of insulin to achieve glycemic control.

Healthday Renal biomarkers predict adverse outcomes in diabetes

Renal biomarkers predict adverse outcomes in diabetes

Three renal biomarkers - AKI, albuminuria, and eGFR - can predict adverse outcomes in diabetes, according to a study published in Diabetes Care.

News Smoking is associated with
 high risk of type 2 diabetes

Smoking is associated with
 high risk of type 2 diabetes

A meta-analysis of 88 studies show a concrete link between current smokers and an elevated risk of type 2 diabetes.

News USPSTF recommends new screening guidelines for type 2 diabetes

USPSTF recommends new screening guidelines for type 2 diabetes

Clinicians should screen all asymptomatic, obese adults for abnormal blood glucose levels, says the U.S. Preventative Services Task Force.

News Long naps, daytime sleepiness may increase type 2 diabetes risk

Long naps, daytime sleepiness may increase type 2 diabetes risk

Daytime sleepiness and long naps may be associated with significantly increased risks of developing type 2 diabetes.

Healthday Half of U.S. adults have type 2 diabetes or prediabetes

Half of U.S. adults have type 2 diabetes or prediabetes

Almost half of adults in the United States have either type 2 diabetes or prediabetes, though many are undiagnosed.

Feature SGLT2 receptor blockers 
for diabetes

SGLT2 receptor blockers 
for diabetes


SGLT2 receptor blockers are only approved for type 2 diabetes.

News Combination drug for adults with type 2 diabetes mellitus

Combination drug for adults with type 2 diabetes mellitus

Glyxambi is adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus when treatment with both empagliflozin and linagliptin is appropriate.

Healthday DPP-4 inhibitors may cause severe joint pain in type 2 diabetes

DPP-4 inhibitors may cause severe joint pain in type 2 diabetes

The FDA released a warning that DPP-4 inhibitors may lead to severe joint pain in patients with T2DM.

Healthday Diabetes insulin type does not affect myocardial infarction risk

Diabetes insulin type does not affect myocardial infarction risk

Using long-acting insulin in type 2 diabetes does not increase the risk for acute myocardial infarction.

Healthday Eating breakfast helps control glucose in type 2 diabetes

Eating breakfast helps control glucose in type 2 diabetes

People with type 2 diabetes who skipped breakfast had a higher risk of postprandial hyperglycemia.

Healthday Eating carbs last in a meal lowers glucose levels

Eating carbs last in a meal lowers glucose levels

Eating carbohydrates last helped lower glucose levels, especially if vegetables and proteins were eaten first.

Healthday Diabetes may increase infection-related mortality risk

Diabetes may increase infection-related mortality risk

After adjustment for age and sex, standardized mortality ratios (SMRs) were higher in type 1 and type 2 diabetes for all outcomes.

News Older insulins may be option for uninsured patients with diabetes

Older insulins may be option for uninsured patients with diabetes

Current insulin treatments and new agents to manage diabetes may be prohibitively expensive for patients without health insurance.

News Simple practice changes help improve glycemic control

Simple practice changes help improve glycemic control

Creating better long-term, sustained relationship between patients and providers improves patient satisfaction and adherence to treatment.

Healthday Gastritis tied to metformin-related gastrointestinal side effects in type 2 diabetes

Gastritis tied to metformin-related gastrointestinal side effects in type 2 diabetes

With metformin, mean score for gastrointestinal side effects higher for gastritis subjects over four weeks.

Healthday Strict glycemic control may decrease cardiovascular events in diabetes patients

Strict glycemic control may decrease cardiovascular events in diabetes patients

The glycated hemoglobin in the intensive control group was 6.9%, on average. For those on standard care, the glycated hemoglobin average was 8.4%.

Healthday Vegan diet may improve diabetic neuropathy pain

Vegan diet may improve diabetic neuropathy pain

The vegan group had lost 15 pounds, on average, versus about one pound in the comparison group.

News Educate patients on SGLT2 inhibitors about yeast infection risk

Educate patients on SGLT2 inhibitors about yeast infection risk

Patients with diabetes who are prescribed sodium glucose co-transporter type 2 inhibitors are at increased risk for developing a mycotic infection.

News Overweight patients with type 2 diabetes may have lower mortality risk

Overweight patients with type 2 diabetes may have lower mortality risk

Although overweight patients were more likely to develop heart disease, overweight patients, however, were less likely to die, compared with obese and normal-weight individuals.

Healthday One fewer sugary drink a day cuts diabetes risk

One fewer sugary drink a day cuts diabetes risk

Drinking water, unsweetened tea or coffee instead lowered risk by 25%.

Healthday Type 2 diabetes screening does not improve mortality rates

Type 2 diabetes screening does not improve mortality rates

Treatment of impaired fasting glucose, impaired glucose tolerance can delay progression to diabetes.

Healthday Assessing third-line treatment options for type 2 diabetes

Assessing third-line treatment options for type 2 diabetes

Add-on thiazolidinedione decreased HbA1c significantly better than add-on glimepiride among patients inadequately controlled on metformin + exenatide, but there were significant increases in BMI and systolic blood pressure.

Healthday Lifestyle interventions for diabetes yield modest weight loss results

Lifestyle interventions for diabetes yield modest weight loss results

From all 10 lifestyle intervention groups, the pooled within-group effect on weight (3,063 patients) was −5.33 kg.

Healthday Moderate alcohol intake may cut fasting insulin

Moderate alcohol intake may cut fasting insulin

Alcohol consumption did not influence estimated insulin sensitivity or fasting glucose but was correlated with reductions in HbA1c and fasting insulin concentrations.

Healthday Diabetes may worsen breast cancer diagnosis

Diabetes may worsen breast cancer diagnosis

Five-year survival for breast cancer patients with diabetes was 15% lower than for those without diabetes.

Healthday Certain antibiotics may boost type 2 diabetes risk

Certain antibiotics may boost type 2 diabetes risk

Patients who were prescribed at least two courses of four types of antibiotics -- penicillins, cephalosporins, quinolones, and macrolides -- were more likely to develop diabetes.

News Intensive weight management, bariatric surgery yield similar results in type 2 diabetes

Intensive weight management, bariatric surgery yield similar results in type 2 diabetes

Both bariatric surgery and intensive weight management yielded similar improvements in HbA1c, weight loss and quality of life.

News Losing 30 minutes of sleep may increase obesity risk

Losing 30 minutes of sleep may increase obesity risk

For every 30 minutes of lost weekday sleep, the risk of obesity and insulin resistance increased substantially.

Feature Transplant, steroids, and diabetes: Inpatient and outpatient management

Transplant, steroids, and diabetes: Inpatient and outpatient management

A patient, aged 60 years, was admitted to the hospital to undergo renal transplant therapy. He had a history of type 2 diabetes for 15 years.

Healthday AMA, CDC to focus on diabetes prevention

AMA, CDC to focus on diabetes prevention

Testing Americans at risk for type 2 diabetes is the first step, experts said.

Healthday Obese kids may be at even greater risk of cardiovascular disease than previously thought

Obese kids may be at even greater risk of cardiovascular disease than previously thought

About half of the children enrolled in the study had elevated blood pressure or dyslipidemia, and 14% had diabetes.

News GLP-1 receptor agonist for 
type 2 diabetes

GLP-1 receptor agonist for 
type 2 diabetes

Not recommended as first-line treatment for patients inadequately controlled on diet and exercise.

News Combination drug 
for type 2 diabetes

Combination drug 
for type 2 diabetes

Adjunct to diet and exercise to improve glycemic control in adults with T2DM who are not adequately controlled on a regimen containing metformin or canagliflozin.

Healthday Childhood body mass index may influence type 2 diabetes risk

Childhood body mass index may influence type 2 diabetes risk

Two pathways of child growth that were associated with the development of T2D, found the researchers.

Feature Transitioning a patient with a complex insulin regimen from hospital to home

Transitioning a patient with a complex insulin regimen from hospital to home

When creating outpatient diabetes management plan, the patient's inpatient medication regimen should be considered but not necessarily replicated.

Feature Updated recommendations for managing hyperglycemia in type 2 diabetes

Updated recommendations for managing hyperglycemia in type 2 diabetes

In 2012, the ADA and the EASD published a position statement on the management of hyperglycemia in patients with T2DM. In January, 2015, the ADA and EASD issued an update to the original 2012 statement.

Healthday Consider high-fiber diets for patients who have difficulty following diet plans

Consider high-fiber diets for patients who have difficulty following diet plans

The average weight loss after a year was about 6 pounds for the AHA dieters and 4.6 pounds for the high-fiber followers, but all of the participants experienced lower blood pressure and reduced blood glucose levels.

Healthday Blood pressure meds benefit type 2 diabetes patients

Blood pressure meds benefit type 2 diabetes patients

Each decrease of 10 mm mercury (Hg) in systolic blood pressure reading reduced the risk of early death by 13%.

News Post-traumatic stress disorder ups diabetes risk in women

Post-traumatic stress disorder ups diabetes risk in women

The greater the number and severity of post-traumatic stress disorder symptoms, the greater a patient's risk of type 2 diabetes.

News Empagliflozin/linagliptin tablets approved for type 2 diabetes

Empagliflozin/linagliptin tablets approved for type 2 diabetes

The FDA has approved empagliflozin/linagliptin tablets as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes when both empagliflozin and linagliptin are appropriate treatments.

Healthday Added fructose: a chief driver of type 2 diabetes?

Added fructose: a chief driver of type 2 diabetes?

Reducing the intake of added sugars may help reduce diabetes-related morbidity, researchers suggest.

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