Web Exclusives

PAH Risk, Mortality Increased by Disturbances in Male Sex Hormones

PAH Risk, Mortality Increased by Disturbances in Male Sex Hormones

Men with higher estradiol and estradiol/testosterone levels had an increased risk for pulmonary arterial hypertension.

Effects of the Two Types of Anorexia Nervosa on Bone Metabolism

Effects of the Two Types of Anorexia Nervosa on Bone Metabolism

Investigators sought to determine whether both restrictive and purging types of anorexia nervosa effect bone metabolism.

Prolonged Exposure to Psychotropic Medications Common in Medicaid-Insured Children

Prolonged Exposure to Psychotropic Medications Common in Medicaid-Insured Children

Researchers emphasized the need for outcomes research in pediatric populations to elucidate the long-term effects of early and sustained psychotropic medication exposure.

Diethylstilbestrol Use in Pregnancy Linked to Multigenerational Neurodevelopmental Deficits

Diethylstilbestrol Use in Pregnancy Linked to Multigenerational Neurodevelopmental Deficits

Diethylstilbestrol exposure during pregnancy is associated with multigenerational neurodevelopmental deficits in childhood, including ADHD.

First-of-Its-Kind Migraine Drug Receives FDA Approval

First-of-Its-Kind Migraine Drug Receives FDA Approval

The efficacy of Aimovig was evaluated as a preventive treatment of episodic or chronic migraine in 3 randomized, double-blind, placebo-controlled studies: 2 studies in patients with episodic migraine (4-14 migraine days per month) and 1 study in patients with chronic migraine (≥15 headache days per month with ≥8 migraine days per month).

Adding Chiropractic to Usual Care Beneficial for Low Back Pain

Adding Chiropractic to Usual Care Beneficial for Low Back Pain

Improvements in low back pain intensity and disability among active-duty military personnel

Preprofessional Program After High School Beneficial for PA Students

Preprofessional Program After High School Beneficial for PA Students

Students who enter a preprofessional program directly after high school may be successful in PA school with structure, guidance, and mentorship.

Do Clinicians Practice What They Preach to Patients?

Do Clinicians Practice What They Preach to Patients?

There are inconsistencies between patient education and healthcare provider practices, which vary in each health maintenance factor.

AAPA Launches Primary Care Obesity Management Certificate Program

AAPA Launches Primary Care Obesity Management Certificate Program

The new program, announced by AAPA, will allow its participants to obtain 30 CME credits and an OMA-issued Certificate of Primary-Care Obesity Management after completion.

Geriatric Workforce Shortage Creates Opportunities for PAs

Geriatric Workforce Shortage Creates Opportunities for PAs

The geriatric workforce shortage may provide PAs with opportunities to engage themselves in the specialty.

Hand Grip Strength Associated With All-Cause Mortality, Other Adverse Outcomes

Hand Grip Strength Associated With All-Cause Mortality, Other Adverse Outcomes

Grip strength is strongly and inversely associated with all-cause mortality and incidence of and mortality from cardiovascular disease, respiratory disease, COPD, all cancer, and subtypes of cancer, with associations being modestly stronger in the younger age groups.

Increased Collaboration, Shared Decision Making Beneficial for Patients With Type 2 Diabetes

Increased Collaboration, Shared Decision Making Beneficial for Patients With Type 2 Diabetes

Patients with T2DM adhere better to self-management behaviors and may experience greater treatment satisfaction if they have increased collaboration and shared decision making with an advanced care provider.

New PA Programs and Their Effect on Established Medical Institutions

New PA Programs and Their Effect on Established Medical Institutions

Newly developed PA programs may be influenced by current APN programs of the same institution.

AAPA's House of Delegates Votes to Investigate Changing Physician Assistant Title

AAPA's House of Delegates Votes to Investigate Changing Physician Assistant Title

Members of the AAPA's House of Delegates voted to investigate the feasibility of changing the physician assistant title, as well as collaborate on potential alternatives that better reflect modern PA practice.

Obesity Treatment Education, Training Needed in PA Programs

Obesity Treatment Education, Training Needed in PA Programs

Recognizing the obesity epidemic and educating physician assistants on the implications of this condition and how they should be caring for obese patients should be prioritized, according to the study authors.

PAs Improving in Providing Dental Health Care

PAs Improving in Providing Dental Health Care

Educating certified PAs to incorporate oral health as an important addition to health care can help bring quality care to more patients with dental needs.

Optimal Team Practice: A Survey of Physician Opinions

Optimal Team Practice: A Survey of Physician Opinions

In 2017, the AMA declared its opposition to autonomous PA regulatory boards and PA practice without physician supervision, but physicians' opinions on OTP policy have been largely unknown.

Childhood-Onset Bipolar Disorder Associated With Impaired Family Functioning

Childhood-Onset Bipolar Disorder Associated With Impaired Family Functioning

Further investigation into the family-based mechanisms of childhood-onset bipolar disorder may assist in the development of future targeted, effective therapies.

Pharmaceutical Marketing Associated With Increased Opioid Prescription Rates

Pharmaceutical Marketing Associated With Increased Opioid Prescription Rates

Payments correlated with prescribing opioids in 2014 may have influenced the increased prescription rates of 2015.

Patients with Frontal Chronic Headaches May Benefit from Endoscopic Decompression Surgery

Patients with Frontal Chronic Headaches May Benefit from Endoscopic Decompression Surgery

Oral medication, botulinum toxin type A injections, and endoscopic decompression surgery were all compared in the treatment of patients with frontal secondary headaches due to STN and SON configuration.

A Model for Nurse Practitioner-Physician Comanagement

A Model for Nurse Practitioner-Physician Comanagement

Nurse practitioner and physician comanagement in primary care has 3 vital attributes: effective communication; mutual respect and trust; and clinical alignment, also known as a shared philosophy of care.

Caucasian, First-Year PA Students Have Lower Levels of Perceived Cultural Competence

Caucasian, First-Year PA Students Have Lower Levels of Perceived Cultural Competence

Caucasian students and first-year students have lower levels of perceived cultural competence, and these students believe that they were moderately or well prepared to care for diverse patient populations.

Opioid Education Program Boosts PA Students' Confidence in Providing Patient Care

Opioid Education Program Boosts PA Students' Confidence in Providing Patient Care

PA students perceived improved confidence in their ability to provide patient education and counseling.

Naloxone Training Beneficial for PA Students

Naloxone Training Beneficial for PA Students

Opioid-specific health seminars may help PA students learn lifesaving treatments to perform in the future.

Early Hospital Readmissions More Preventable Than Late Readmissions

Early Hospital Readmissions More Preventable Than Late Readmissions

Can the length of time after hospital discharge influence readmission preventability among general medicine patients?

Psychological Interventions Beneficial for Chronic Pain in Older Adults

Psychological Interventions Beneficial for Chronic Pain in Older Adults

Researchers found a positive but weak correlation between psychological interventions and chronic pain treatment in older adults.

Electrical Device Helps Reduce Daily Salt Intake, Improve Blood Pressure

Electrical Device Helps Reduce Daily Salt Intake, Improve Blood Pressure

Using a simple self-monitoring device may help reduce salt intake and systolic blood pressure.

AAPA Responds to JAMA Dermatology Study

AAPA Responds to JAMA Dermatology Study

AAPA and SDPA respond to a recent article published in JAMA Dermatology.

Visual Test Improves Prediction of Dementia in Primary Care

Visual Test Improves Prediction of Dementia in Primary Care

Administering a visual association test in patients with a small decline on the Mini-Mental State Examination during a 2-year period has substantial incremental value for identifying those at elevated risk for developing dementia.

Stroke, TIA Risk Remain High After Atrial Fibrillation Resolved

Stroke, TIA Risk Remain High After Atrial Fibrillation Resolved

Patients with resolved atrial fibrillation have an increased risk for stroke or transient ischemic attack.

Seasonal Allergies: Treatment Tips From the FDA

Seasonal Allergies: Treatment Tips From the FDA

The US Food & Drug Administration (FDA) has released updated tips for the treatment of seasonal allergies.

Ovarian Cancer Patients May Benefit From Trabectedin With PLD

Ovarian Cancer Patients May Benefit From Trabectedin With PLD

For patients with platinum-sensitive recurrent ovarian cancer, trabectedin plus PLD may be beneficial.

Prevalence of Obese, Allergic Asthma Phenotypes Examined in US Children

Prevalence of Obese, Allergic Asthma Phenotypes Examined in US Children

The study authors examined data obtained from the 2007-2008 National Survey of Children's Health (NSCH) to determine the prevalence, risk factors, as well as the severity of asthma phenotypes.

Increased Water Consumption Does Not Enhance Kidney Function in Chronic Kidney Disease

Increased Water Consumption Does Not Enhance Kidney Function in Chronic Kidney Disease

Trained water consumption increase does not significantly reduce the decline of kidney function in individuals with chronic kidney disease.

Highly Selective, First-in-Class CDK4 Inhibitor Promising in Ovarian Cancer

Highly Selective, First-in-Class CDK4 Inhibitor Promising in Ovarian Cancer

Mice treated with 2-94 had few or no signs of lymphopenia or neutropenia, common adverse events associated with palbociclib.

Personalized Cancer Vaccine Looks Promising in Early Study

Personalized Cancer Vaccine Looks Promising in Early Study

The researchers enrolled 25 platinum-pretreated, immunotherapy-naïve patients with recurrent advanced epithelial ovarian cancer (EOC) for the trial.

Preterm Infant Vitamin D Level Affects Calcium and Bone Health

Preterm Infant Vitamin D Level Affects Calcium and Bone Health

Vitamin D levels in preterm infants are significantly correlated with optimal calcium homeostasis and bone mineralization of the femur.

PAs Have Lower Diagnostic Accuracy for Melanoma Compared With Dermatologists

PAs Have Lower Diagnostic Accuracy for Melanoma Compared With Dermatologists

Compared with dermatologists, physician assistants perform more skin biopsies but detect fewer melanomas.

Rheumatology Curriculum Outline Aims to Train and Integrate NPs and PAs

Rheumatology Curriculum Outline Aims to Train and Integrate NPs and PAs

The ACR/ ARHP created a rheumatology curriculum outline that can be used to create more efficient integration of NPs and PAs into rheumatology practice.

Screening for Prostate Cancer: USPSTF Recommendation Statement

Screening for Prostate Cancer: USPSTF Recommendation Statement

The USPSTF has updated its 2012 recommendations on prostate-specific antigen (PSA)-based screening for prostate cancer.

Some Anticholinergic Drugs May Be Linked to Dementia

Some Anticholinergic Drugs May Be Linked to Dementia

Anticholinergic drugs for depression, urologic conditions, or Parkinson disease are associated with potential dementia occurrences up to 20 years after drug exposure.

Discerning Arterial Ischemic Stroke From Migraine in Pediatric Emergency Departments

Discerning Arterial Ischemic Stroke From Migraine in Pediatric Emergency Departments

Investigators examined presenting features of migraine vs arterial ischemic stroke in children presenting to the emergency department.

Case Study: Cardiovascular Complications of Chronic Obstructive Pulmonary Disease

Case Study: Cardiovascular Complications of Chronic Obstructive Pulmonary Disease

A 55-year-old man with chronic obstructive pulmonary disease reports having some mild chest pain.

eConsult in Primary Care: Clinicians Surveyed About the Pros and Cons

eConsult in Primary Care: Clinicians Surveyed About the Pros and Cons

Implementing an electronic consult system for specialty requests in safety-net health systems is associated with improved specialty care access but creates new challenges for primary care practitioners.

Dark Chocolate Linked to Enhanced Visual Acuity

Dark Chocolate Linked to Enhanced Visual Acuity

Compared with milk chocolate, dark chocolate was associated with improved low, high-contrast sensitivity and visual acuity in short durations.

Pain, Psychiatric Comorbidities More Common in Chronic vs Episodic Migraine

Pain, Psychiatric Comorbidities More Common in Chronic vs Episodic Migraine

Individuals with chronic vs episodic migraine may be more likely to experience chronic back pain, chronic pain, neck pain, anxiety, and depression.

Parkinson Drug May Be Linked to Deaths

Parkinson Drug May Be Linked to Deaths

The FDA advisory committee voted 12-2 in favor of recommending the approval of Nuplazid.

Vitamin D Insufficiency Associated With Insulin Resistance Independent of Obesity in Children

Vitamin D Insufficiency Associated With Insulin Resistance Independent of Obesity in Children

Further clinical trials are needed to explore the potential beneficial effect of vitamin D supplementation, via fortified foods and/or dietary supplements, on insulin resistance, and possibly on weight management.

Cannabis Use, Cognitive Functioning Link Small in Adolescents, Young Adults

Cannabis Use, Cognitive Functioning Link Small in Adolescents, Young Adults

Associations between cannabis use and cognitive functioning in adolescents and young adults are small.

Intrathecal Drug Delivery and Spinal Cord Stimulation for Cancer Pain: A Review

Intrathecal Drug Delivery and Spinal Cord Stimulation for Cancer Pain: A Review

Intrathecal drug delivery systems and spinal cord stimulation have shown promise for the treatment of cancer pain in initial studies.

NP, PA Employment Increasing in Primary Care and Specialty Practices

NP, PA Employment Increasing in Primary Care and Specialty Practices

The proportion of practices with NPs and PAs increased modestly from 2008 to 2016, with similar growth found in specialty and primary care practices.

Case Report: Nephrotic Syndrome and Chronic HCV in a 72-Year-Old Woman

Case Report: Nephrotic Syndrome and Chronic HCV in a 72-Year-Old Woman

A 72-year-old Japanese woman with a 40-year history of lupus nephritis presented with leg edema that had lasted for several weeks.

Combining Spinal Manipulation and Exercise for Low Back Pain in Adolescents

Combining Spinal Manipulation and Exercise for Low Back Pain in Adolescents

A combination of self-care education, aerobic and strength-training exercise, and spinal manipulation therapy may provide greater pain relief and improved treatment satisfaction compared with exercise only in adolescents with low back pain.

ACOG: Updated Recommendations for Influenza Vaccination During Pregnancy

ACOG: Updated Recommendations for Influenza Vaccination During Pregnancy

This updated Committee Opinion includes more recent data on the safety and efficacy of influenza vaccination during pregnancy, as well as recommendations for treatment and postexposure chemoprophylaxis.

Artificial Pancreas Systems Safe, Effective in Type 1 Diabetes

Artificial Pancreas Systems Safe, Effective in Type 1 Diabetes

Artificial pancreas treatments are safe and effective for managing type 1 diabetes.

More Comprehensive HDV Surveillance Needed in High-Risk Individuals

More Comprehensive HDV Surveillance Needed in High-Risk Individuals

Future studies might focus on the use of electronic medical record warning systems or other prompts to improve diagnostic test use in at-risk individuals.

Intraoperative Opioid Doses and Rates of Hospital Readmission

Intraoperative Opioid Doses and Rates of Hospital Readmission

The use of high doses of opioids — particularly long-acting opioids — during surgery may increase the risk for 30-day readmission.

Gene Therapy May Eliminate Blood Transfusion Needs in Severe β-Thalassemia

Gene Therapy May Eliminate Blood Transfusion Needs in Severe β-Thalassemia

With use of CD34+ cells via BB305 vector transduction, patients with severe β-thalassemia may no longer require long-term RBC transfusions as frequently or at all.

Headache in Older Adults: Unique Causes and Treatments

Headache in Older Adults: Unique Causes and Treatments

It is important for clinicians to quickly and accurately determine potential underlying causes and to prescribe treatments that take into account comorbidities and medications that older patients may be taking for them.

USPSTF Recommends Screening for Partner Violence in Reproductive-Aged Women

USPSTF Recommends Screening for Partner Violence in Reproductive-Aged Women

The USPSTF has found that screening for intimate partner violence is beneficial for reproductive-aged women, although there is inadequate evidence to weigh the balance of benefits and harms of screening for abuse in elderly and vulnerable adults.

Diabetes and Mortality: Comparing SGLT-2 Inhibitors, GLP-1 Agonists, and DPP-4 Inhibitors

Diabetes and Mortality: Comparing SGLT-2 Inhibitors, GLP-1 Agonists, and DPP-4 Inhibitors

For patients with type 2 diabetes, sodium-glucose cotransporter 2 inhibitors and glucagon-like peptide 1 agonists significantly reduce mortality rates compared with dipeptidyl peptidase 4 inhibitors.

Multiple Sclerosis Guidelines: AAN's Recommendations for Initiating, Switching, Stopping Disease-Modifying Therapy

Multiple Sclerosis Guidelines: AAN's Recommendations for Initiating, Switching, Stopping Disease-Modifying Therapy

The new guidelines focus on helping clinicians decide when to initiate, switch, or discontinue disease-modifying therapies for multiple sclerosis.

Early Child Care Attendance and Asthma, Wheeze Risk: Is There a Link?

Early Child Care Attendance and Asthma, Wheeze Risk: Is There a Link?

Early child care attendance increased the risk for wheeze in children ≤2 years of age but decreased the risk for asthma in children 3 to 5 years of age.

Autism Linked to Prenatal Ultrasonography Depth

Autism Linked to Prenatal Ultrasonography Depth

No statistically significant difference was observed in the number or duration of prenatal ultrasonographic scans across the entire pregnancy in children with later autism compared with controls with non-ASD developmental delay or typical development.

Diabetes Prevalence by Type in the United States: CDC report

Diabetes Prevalence by Type in the United States: CDC report

The CDC conducted a study to estimate the prevalence of diagnosed diabetes among adults in 2016 by primary type.

Epilepsy Associated With Increased Risk of Unnatural Death

Epilepsy Associated With Increased Risk of Unnatural Death

Patients with epilepsy have a greater risk of unnatural mortality than individuals without the disorder and should take greater precautions when taking certain medications.

Helping to End Addiction: NIH Initiative Addresses Opioid Epidemic

Helping to End Addiction: NIH Initiative Addresses Opioid Epidemic

National Institutes of Health Director, Francis Collins, MD, PhD, announced on April 4, 2018 the launch of the Helping to End Addiction Long-Term Initiative.

Bully for Us: Confronting Medicine's Bullying Problem

Bully for Us: Confronting Medicine's Bullying Problem

The culture of bullying — widespread across the medical field — has been linked to poorer patient outcomes. So why can't physicians stop bullying in its tracks?

Switching from Branded to Authorized Generic Drugs Linked to Lower Switchback Rate

Switching from Branded to Authorized Generic Drugs Linked to Lower Switchback Rate

Switching back to branded drugs is more likely in generic drug than authorized generic drugs.

Study Finds Safe Alcohol Consumption Guidelines May Not Be Strict Enough

Study Finds Safe Alcohol Consumption Guidelines May Not Be Strict Enough

Among current drinkers without previous diagnosis of cardiovascular disease, the threshold for lowest risk of all-cause mortality is about 100 g of alcohol consumed per week.

COPD Risk in Middle Age: The 3-Way Interaction of Asthma, Smoking, and Childhood Measles

COPD Risk in Middle Age: The 3-Way Interaction of Asthma, Smoking, and Childhood Measles

A childhood measles infection may increase the risk for post-bronchodilator airflow obstruction in middle-age adults via its interaction with asthma and smoking.

USPSTF Issues Recommendation for Vitamin D, Calcium Supplementation for Fracture Prevention

USPSTF Issues Recommendation for Vitamin D, Calcium Supplementation for Fracture Prevention

The USPSTF has released recommendations for vitamin D and calcium supplementation for the primary prevention of fractures in community-dwelling adults.

CBT vs Pain Education for Chronic Pain in Low-Income Clinics

CBT vs Pain Education for Chronic Pain in Low-Income Clinics

Group cognitive behavioral therapy and pain education may be more effective than usual care for improving pain and physical function in patients presenting with chronic pain at low-income clinics.

Alcohol-related Nurse Care Ineffective in Heavy Drinkers

Alcohol-related Nurse Care Ineffective in Heavy Drinkers

CHOICE intervention for patients with high risk for alcohol use disorder may not reduce heavy drinking or associated problems.

Siponimod Reduces Risk for Disability Progression in Secondary Progressive MS

Siponimod Reduces Risk for Disability Progression in Secondary Progressive MS

Investigators believe the siponimod EXPAND study is the first trial of disease-modifying therapy to show superiority over a placebo for disability progression in SPMS.

Tai Chi May Be Therapeutic Option for Fibromyalgia

Tai Chi May Be Therapeutic Option for Fibromyalgia

Tai chi interventions may be more effective at treating fibromyalgia than aerobic exercise.

Advanced Ovarian Cancer Survival Rates Longer After Primary Cytoreductive Surgery Compared With Neoadjuvant Chemotherapy

Advanced Ovarian Cancer Survival Rates Longer After Primary Cytoreductive Surgery Compared With Neoadjuvant Chemotherapy

Researchers found a superior survival rate in patients who received primary cytoreductive surgery as opposed to neoadjuvant chemotherapy for stage IIIC and IV high-grade serous ovarian carcinoma.

Newly Proposed Definition of Alzheimer's Disease Focuses on Biologic Criteria

Newly Proposed Definition of Alzheimer's Disease Focuses on Biologic Criteria

The NIA-AA has proposed updates to the 2011 guidelines for symptomatic stages of Alzheimer's disease to include the idea that certain imaging and cerebrospinal fluid biomarkers are valid proxies for neuropathologic changes of AD.

FDA: Social Media Companies Are Not Doing Enough to Stop Illegal Opioid Sales

FDA: Social Media Companies Are Not Doing Enough to Stop Illegal Opioid Sales

FDA has called on social media companies and internet service providers to take a proactive approach in curbing online selling of opioids through their platforms.

FDA Approves Multi-Cancer Treatment Drug

FDA Approves Multi-Cancer Treatment Drug

The FDA has approved Rubraca, a poly (ADP-ribose) polymerase inhibitor, to treat patients with epithelial ovarian, fallopian tube, or primary peritoneal cancer.

Effectiveness of Shortened Treatment Regimen for Hepatitis C Assessed

Effectiveness of Shortened Treatment Regimen for Hepatitis C Assessed

In this large, real-world cohort of patients with chronic hepatitis C virus infection, equivalent sustained virologic response rates were found with both 8-week and 12-week treatment.

Infant Use of Acid-Suppressants, Antibiotics Tied to Allergic Disease Development

Infant Use of Acid-Suppressants, Antibiotics Tied to Allergic Disease Development

Some allergic diseases associated with acid-suppressive, antibiotic intake in infants younger than 6 months old include food allergies, anaphylaxis, asthma, and allergic rhinitis.

End-of-Treatment HBsAg Levels May Predict HBV Relapse in Chronic Hepatitis B

End-of-Treatment HBsAg Levels May Predict HBV Relapse in Chronic Hepatitis B

End-of-treatment HBsAg levels may be a clinically useful biomarker to predict HBV relapse in patients with chronic hepatitis B regardless of HBeAg status.

In Utero Exposure to Multiple AEDs, Sodium Valproate Linked to Poor Educational Attainment in Childhood

In Utero Exposure to Multiple AEDs, Sodium Valproate Linked to Poor Educational Attainment in Childhood

In utero exposure to AEDs in combination, or sodium valproate alone, is associated with a significant decrease in attainment in national educational tests for 7-year-old children.

Code Stroke System Reduces Post-Stroke Epilepsy Risk in Older Adults

Code Stroke System Reduces Post-Stroke Epilepsy Risk in Older Adults

The adjusted analysis also demonstrated that the code stroke system was associated with a decreased risk for post-stroke epilepsy within 5 years of stroke.

Fycompa sNDA Submitted for Pediatric Seizure Indications

Fycompa sNDA Submitted for Pediatric Seizure Indications

The proposed pediatric indications are based on a 2018 Draft Guidance that supports extrapolating efficacy data of approved drugs to treat POS in adults to pediatric patients aged ≥4 years.

Maternal Probiotic, Fish Oil Intake Linked to Offspring Immune Development

Maternal Probiotic, Fish Oil Intake Linked to Offspring Immune Development

Maternal diet may be correlated with certain autoimmune-associated diseases in offspring.

Direct-Acting Antivirals Improve Liver Transplant Survival

Direct-Acting Antivirals Improve Liver Transplant Survival

Direct-acting antivirals improved the survival of patients undergoing liver transplantation for HCV-related liver disease.

Antibiotic-Resistant Bacteria Found in 221 US Healthcare Facilities in 2017

Antibiotic-Resistant Bacteria Found in 221 US Healthcare Facilities in 2017

Antibiotic resistance is a nationwide issue that affects every state, so how do we combat it?

CVS unintentionally reveals HIV status of 6,000 customers, per lawsuit

CVS unintentionally reveals HIV status of 6,000 customers, per lawsuit

CVS Health faces lawsuit for revealing the HIV status of 6,000 patients in Ohio.

FDA approves antiretroviral therapy for multidrug-resistant HIV

FDA approves antiretroviral therapy for multidrug-resistant HIV

The FDA has approved Trogarzo for heavily treated adult patients living with HIV and whose HIV infections cannot be successfully treated with other currently available therapies.

Pink Eye: Prevention and Treatment Tips from the CDC

Pink Eye: Prevention and Treatment Tips from the CDC

Pink eye, also known as conjunctivitis, is an inflammation of the conjunctiva.

Pediatric irritability, depressive moods linked to suicidality in adolescence

Pediatric irritability, depressive moods linked to suicidality in adolescence

Children with chronic irritability, including depressive or anxious moods, may be at an increased risk for suicidality or suicidal thoughts as adolescents.

Daily dose of PrEP raises coverage, protective drug concentrations

Daily dose of PrEP raises coverage, protective drug concentrations

Recommendations for daily doses of emtricitabine (FTC)/tenofovir disoproxil fumarate (TDF) resulted in protective drug concentrations for men and transgender women.

Pediatric Asthma Unaffected by 5-fold Increased Inhaled Glucocorticoid Dose

Pediatric Asthma Unaffected by 5-fold Increased Inhaled Glucocorticoid Dose

Increasing inhaled glucocorticoid doses at initial signs of exacerbating asthma may not be effective.

Antidepressant Types Linked to Different Adverse Outcomes in Adults with Depression

Antidepressant Types Linked to Different Adverse Outcomes in Adults with Depression

Selective serotonin reuptake inhibitors and other antidepressants, such as tricyclic antidepressants, are associated with increased adverse outcomes in patients aged 20 to 64 years diagnosed with depression.

Prostate-specific antigen screening helps prostate cancer detection

Prostate-specific antigen screening helps prostate cancer detection

Prostate cancer was diagnosed more frequently in men who underwent single prostate-specific antigen screening than in those who did not, but mortality was unaffected.

Behavioral Counseling for Skin Cancer Prevention: USPSTF Updated Recommendations

Behavioral Counseling for Skin Cancer Prevention: USPSTF Updated Recommendations

The USPSTF has updated both the 2012 recommendation on behavioral counseling for the primary prevention of skin cancer and the 2009 recommendation on screening for skin cancer with skin self-examination.

Cannabinoids May Decrease Seizure Frequency in Refractory Epilepsy

Cannabinoids May Decrease Seizure Frequency in Refractory Epilepsy

A reasonable proportion of patients with epilepsy who have received treatment with pharmaceutical-grade cannabidiol products along with antiepileptic drugs have experienced a decrease in seizure frequency.

DSM-5 major depressive disorder diagnosis prevalence still high in US

DSM-5 major depressive disorder diagnosis prevalence still high in US

Investigators sought to determine the national prevalence of adults with a major depressive disorder diagnosis according to DSM-5 from 2012 to 2013.

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