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FDA to Review Gimoti for Diabetic Gastroparesis in Adult Women

FDA to Review Gimoti for Diabetic Gastroparesis in Adult Women

The FDA has set a Prescription Drug User Fee Act target date of April 1, 2019.

First Generic Version of EpiPen Gets FDA Approval

First Generic Version of EpiPen Gets FDA Approval

Unlike other generic approvals, epinephrine auto-injectors are considered "combination products" because they consist of both a drug and a device, making the approval process more challenging.

AHA/ACC: Updated Management Guidelines for Adult Congenital Heart Disease

AHA/ACC: Updated Management Guidelines for Adult Congenital Heart Disease

The American College of Cardiology and American Heart Association developed updated guidelines on the evaluation, management, and monitoring of adults with congenital heart disease.

Copy Number Abnormalities May Inform Survival, Drug Resistance

Copy Number Abnormalities May Inform Survival, Drug Resistance

For cancers associated with numerous copy number changes, it is difficult to assign disease classifiers and identify useful targets for drug development.

International Antiviral Society-USA Updates Recommendations for HIV Treatment and Prevention

International Antiviral Society-USA Updates Recommendations for HIV Treatment and Prevention

The International Antiviral Society-USA Panel has updated its recommendations for the management and prevention of HIV infection, to reflect the most current data on new treatment regimens and strategies.

In Shocking Opposition, Trump Administration Denies Decades of Breastfeeding Research

In Shocking Opposition, Trump Administration Denies Decades of Breastfeeding Research

In a move that shocked world health officials, the Trump administration indicated its opposition to a resolution intended to encourage breastfeeding among new mothers

Characteristics of Menstrual Cycle Associated With Early Natural Menopause

Characteristics of Menstrual Cycle Associated With Early Natural Menopause

Investigators examined the relationship between menstrual cycle characteristics in adolescence and early adulthood and the risk for early natural menopause.

Low Literacy Self-Management Program for Chronic Pain May Be Effective

Low Literacy Self-Management Program for Chronic Pain May Be Effective

A low-literacy, pain self-management program delivered one-on-one by a health educator or in groups with lectures from experts over a period of 6 months may improve chronic pain outcomes.

Antibiotics Often Unnecessary for Sacral Pressure Ulcers Complicated by Osteomyelitis

Antibiotics Often Unnecessary for Sacral Pressure Ulcers Complicated by Osteomyelitis

A systematic literature review, published in Clinical Infectious Diseases, found no evidence supporting a benefit to antibacterial therapy for osteomyelitis in patients with stage IV sacral pressure ulcers.

Two-Screen Program More Effective for Identifying Congenital Hypothyroidism

Two-Screen Program More Effective for Identifying Congenital Hypothyroidism

There are 14 states that perform a routine second screening in infants at approximately 2 weeks of age.

Low Rates of Syphilis Testing in High-Risk Men Who Are HIV Positive

Low Rates of Syphilis Testing in High-Risk Men Who Are HIV Positive

Close to one-third of sexually active HIV-positive men who have sex with men (MSM) have not received syphilis screening in the past 12 months.

Safety and Immunogenicity of Tdap Vaccine Immunization During Pregnancy

Safety and Immunogenicity of Tdap Vaccine Immunization During Pregnancy

Immunization with Tdap vaccine during pregnancy results in higher levels of antibodies early in infancy but lower levels after the primary vaccine series.

No Impact on Carotid Artery Intima-Media Thickness Following Cessation of Menopausal Hormone Therapy

No Impact on Carotid Artery Intima-Media Thickness Following Cessation of Menopausal Hormone Therapy

A follow-up study from KEEPS found that cessation of menopausal hormone therapy did not change the expected trajectory of carotid artery intima-media thickness over a 3-year period.

Does Bipolar I Disorder Effect the Course of Conduct/Antisocial Personality Disorders in Adolescents?

Does Bipolar I Disorder Effect the Course of Conduct/Antisocial Personality Disorders in Adolescents?

Adolescents with bipolar I disorder whose symptoms are in remission are significantly less likely to experience conduct disorder or antisocial personality disorder.

ADA Releases Updated Guidelines for Managing Pediatric Type 1 Diabetes

ADA Releases Updated Guidelines for Managing Pediatric Type 1 Diabetes

It is critical for us to remember that children are not little adults. Pediatric-onset diabetes is different from adult-onset diabetes due to its distinct epidemiology, pathophysiology, developmental considerations, and response to therapy.

FDA: Improper Use of Rupture of Membranes Tests Linked to Fetal Deaths

FDA: Improper Use of Rupture of Membranes Tests Linked to Fetal Deaths

ROM tests are used to aid in diagnosing ruptured membranes in pregnant women through analysis of vaginal secretions.

Proton Pump Inhibitor Treatment and Aspirin Improve Outcomes in Barrett Esophagus

Proton Pump Inhibitor Treatment and Aspirin Improve Outcomes in Barrett Esophagus

High-dose esomeprazole taken in combination with aspirin may safely and effectively improve outcomes in patients with Barrett esophagus.

Antidepressants and Bleeding Risk: What's the Link?

Antidepressants and Bleeding Risk: What's the Link?

Results showed an increased risk of bleeding with SRIs by 1.16-2.36 times with an even higher 3.17- to 10.9-fold risk with concomitant NSAIDs.

Food Allergies Linked to Reduced Small Airway Function in Children With Asthma

Food Allergies Linked to Reduced Small Airway Function in Children With Asthma

Children and young adults with asthma and multiple food allergies may be at risk for reduced small airway lung function than children with a single food allergy.

Atopic Dermatitis Associated With Impaired Quality of Life, Overall Health

Atopic Dermatitis Associated With Impaired Quality of Life, Overall Health

Research shows that patients diagnosed with atopic dermatitis experience feelings of dissatisfaction with regard to lifestyle, as well as impaired health and wellness.

Chronic Low Back Pain Levels Vary Between Sex and Race

Chronic Low Back Pain Levels Vary Between Sex and Race

Differences exist in race and gender in patients with chronic lower back pain, especially in pain sensitivity and severity due to aftersensations from mechanical punctuate pain and deep muscle hyperalgesia.

Guidelines for Health Initiative-Faith-Based Organization Partnerships

Guidelines for Health Initiative-Faith-Based Organization Partnerships

Often central to communities, faith-based organizations serve as local touchstones for health initiatives and outreach programs.

Ectopic Lipid Deposition and Insulin Resistance Higher in Postmenopausal Women

Ectopic Lipid Deposition and Insulin Resistance Higher in Postmenopausal Women

The insulin sensitivity in post- and premenopausal women along with lipid deposition in the liver and skeletal muscle was examined.

Antirheumatic Medication Management for Orthopedic Surgery: An Interdisciplinary Perspective

Antirheumatic Medication Management for Orthopedic Surgery: An Interdisciplinary Perspective

A rheumatologist and orthopedic surgeon provide an interdisciplinary perspective on the perioperative management of antirheumatic medications in patients undergoing elective orthopedic surgery.

Chronic Cough in Interstitial Lung Disease: More Clinical Trials Needed

Chronic Cough in Interstitial Lung Disease: More Clinical Trials Needed

An expert panel developed suggestions for chronic cough management in interstitial lung disease, but more clinical trials are needed to establish recommendations.

International PCOS Network Issues New Guidelines for Management and Diagnosis of PCOS

International PCOS Network Issues New Guidelines for Management and Diagnosis of PCOS

International evidence-based guidelines include 166 recommendations and practice points to improve health outcomes of women with PCOS.

Effect of Esomeprazole on Prolonging Gestation in Preterm Preeclampsia

Effect of Esomeprazole on Prolonging Gestation in Preterm Preeclampsia

As there is currently no treatment option available to slow the progression of preeclampsia, clinicians assess esomeprazole, a proton pump inhibitor, as a therapeutic candidate for this challenging condition.

Low-Carb Diet May Reduce HbA1c More Than Low-Fat Diet in T2D

Low-Carb Diet May Reduce HbA1c More Than Low-Fat Diet in T2D

Investigators compared low-carbohydrate with low-fat diet on glucose control and other metabolic and anthropometric variables in T2D.

Severe Asthma Risk Increased From Aspergillus fumigatus Sensitization

Severe Asthma Risk Increased From Aspergillus fumigatus Sensitization

Sensitization to Aspergillus fumigatus increased the risk for severe asthma.

Majority of Patients With Liver Metastases From Colorectal Cancer Eligible for Laparoscopy

Majority of Patients With Liver Metastases From Colorectal Cancer Eligible for Laparoscopy

In high-volume centers, patients with liver metastases from colorectal cancer may often be eligible for minimally invasive liver surgery via laparoscopy, thereby reducing potential morbidity risks associated with open surgery.

Ethical Guidelines for Living Donor Transplantation

Ethical Guidelines for Living Donor Transplantation

The Belmont Report provides an appropriate framework for living donor organ transplantation.

10 Things Your Patients Need to Know About Hand, Foot, and Mouth Disease

10 Things Your Patients Need to Know About Hand, Foot, and Mouth Disease

Hand, foot, and mouth disease is a mild viral infection common in children. Here are 10 things your patients need to know about this ailment.

Combined Meningococcal-Tdap Vaccine May Increase Adolescent Vaccination Coverage

Combined Meningococcal-Tdap Vaccine May Increase Adolescent Vaccination Coverage

For adolescents and young adults, the co-administration of quadrivalent meningococcal conjugate vaccine with incorporated tetanus toxoid with diphtheria-tetanus-acellular pertussis vaccine is noninferior to isolated vaccination and does not compromise immunity.

FAST Scores for Functioning Are Meaningful for Recovery in Bipolar Disorder

FAST Scores for Functioning Are Meaningful for Recovery in Bipolar Disorder

There is no distinct cut off for the Functional Assessment Short Test between none, mind, moderate, and severe functional impairment.

Heat-Stable Carbetocin Safe Alternative to Oxytocin for Postpartum Hemorrhage Prevention

Heat-Stable Carbetocin Safe Alternative to Oxytocin for Postpartum Hemorrhage Prevention

Heat-stable carbetocin — an analog of oxytocin — was found to be noninferior to oxytocin in preventing hemorrhage associated with vaginal birth and may be beneficial in low- and middle-income countries.

Asthma Hospitalization Risk in Children From Grass, Weed, and Other Pollens

Asthma Hospitalization Risk in Children From Grass, Weed, and Other Pollens

Grass, other weeds, and unclassified pollen were significantly associated with increased risk for asthma hospitalization in young children.

Food Addiction Phenotype in Obesity Associated With Higher Risk for Mood, Anxiety Disorders

Food Addiction Phenotype in Obesity Associated With Higher Risk for Mood, Anxiety Disorders

The researchers noted that these findings highlight the complexity of obesity as a disease that shares a common etiology with some psychiatric and addictive disorders.

Hepatic Markers Linked to Early Predictors of Type 2 Diabetes Risk in Women

Hepatic Markers Linked to Early Predictors of Type 2 Diabetes Risk in Women

Circulating hepatic markers may predict the risk for diabetes in women.

Ultrasound Beneficial for Diagnosing Pure Clear Cell Carcinoma of the Ovary

Ultrasound Beneficial for Diagnosing Pure Clear Cell Carcinoma of the Ovary

In a multicenter study, researchers used high-quality ultrasound imaging to identify characteristics of pure ovarian clear cell carcinoma.

FDA Approves FreeStyle Libre 14 Day Flash Glucose Monitoring System

FDA Approves FreeStyle Libre 14 Day Flash Glucose Monitoring System

The new Flash Glucose Monitoring System enables patients to wear the sensor for up to 14 days compared with the existing FreeStyle Libre System that was approved for 10-day wear.

Once-Monthly Perseris Approved for the Treatment of Schizophrenia

Once-Monthly Perseris Approved for the Treatment of Schizophrenia

Perseris, an atypical antipsychotic, has an extended-release delivery system that releases sustained levels of risperidone over 1 month.

More Preventive Care Guidelines Linked to Less Preventive Care Utilization

More Preventive Care Guidelines Linked to Less Preventive Care Utilization

An increase in guideline-recommended preventive services may be associated with a decrease in patient utilization of each suggested service, which may have a negative impact on patient life expectancy or quality of life.

Combination Therapies for Low Back Pain, Sciatica May Not Have Added Benefit

Combination Therapies for Low Back Pain, Sciatica May Not Have Added Benefit

There is a lack of evidence supporting the benefits of combination drug therapy over monotherapy for the management of low back pain and sciatica.

EULAR Releases 2018 Guideline on Physical Activity in Inflammatory Arthritis, Osteoarthritis

EULAR Releases 2018 Guideline on Physical Activity in Inflammatory Arthritis, Osteoarthritis

The European League Against Rheumatism has issued their 2018 recommendations for physical activity in patients with inflammatory arthritis and osteoarthritis.

Wide Variations in Opioid Prescribing Practices for Surgical Procedures

Wide Variations in Opioid Prescribing Practices for Surgical Procedures

Variation exists in opioid prescribing practices among clinicians in single-hospital systems, which prompts concern about the potential for opioid overprescribing.

Quality of Life Maintained With Niraparib for Ovarian Cancer

Quality of Life Maintained With Niraparib for Ovarian Cancer

The ENGOT-OV16/NOVA trial showed improvements in progression-free survival in patients with ovarian cancer with and without the germline BRCA mutation.

FDA to Review Novel Opioid Analgesic for Chronic Low Back Pain

FDA to Review Novel Opioid Analgesic for Chronic Low Back Pain

This novel agent has low permeability across the blood-brain barrier, which slows its rate of entry into the brain and reduces dopamine release.

Aspirin, Non-Aspirin NSAID Use May Improve Survival Outcomes in Ovarian Cancer

Aspirin, Non-Aspirin NSAID Use May Improve Survival Outcomes in Ovarian Cancer

Previous studies have suggested that analgesic medicine use may have a protective effect for patients with ovarian cancer.

Nemolizumab Effective for Moderate, Severe Atopic Dermatitis Inadequately Controlled With Topical Therapy

Nemolizumab Effective for Moderate, Severe Atopic Dermatitis Inadequately Controlled With Topical Therapy

For patients with moderate to severe atopic dermatitis inadequately controlled with topical therapies, the anti-IL-31 receptor A humanized monoclonal antibody nemolizumab may provide benefit.

Independent Relationship Between CV Mortality, Oxidative DNA Damage in Type 2 Diabetes

Independent Relationship Between CV Mortality, Oxidative DNA Damage in Type 2 Diabetes

This represents the prospective study confirming an independent relationship between cardiovascular mortality and oxidative DNA damage in type 2 diabetes.

WIC Program Enrollment Linked to Declining Pediatric Obesity

WIC Program Enrollment Linked to Declining Pediatric Obesity

Childhood obesity continues to be a public health issue that requires improved policies and interventions at both the individual and population level.

Rotavirus Vaccination Linked to Decrease in Hospitalizations

Rotavirus Vaccination Linked to Decrease in Hospitalizations

A significant decline in rotavirus disease-associated hospitalization, emergency department visits, and physician office visits was demonstrated in children younger than 5 years following implementation of the rotavirus vaccine.

Effect of Mediterranean Diet Plus Vitamin D3 on Bone Density in Osteoporosis

Effect of Mediterranean Diet Plus Vitamin D3 on Bone Density in Osteoporosis

Investigators examined the effect of consuming a Mediterranean-style diet for 1 year on inflammatory response and bone health in the elderly.

Cognitive Impairment Profiles Differ Between Parkinson's, Alzheimer's

Cognitive Impairment Profiles Differ Between Parkinson's, Alzheimer's

As the neurodegenerative processes of Alzheimer disease and Parkinson disease are different, early cognitive impairment also present differently in these diseases.

Basal Insulin Analogs vs NPH Insulin to Reduce Hypoglycemia-Linked ED Visits in T2D

Basal Insulin Analogs vs NPH Insulin to Reduce Hypoglycemia-Linked ED Visits in T2D

Compared with human neutral protamine Hagedorn insulin, basal insulin analogs do not reduce risk of hypoglycemia-linked ED visits or hospital admissions in T2D.

Updated Diagnostic Guidelines for Eosinophilic Esophagitis: Outcomes From AGREE

Updated Diagnostic Guidelines for Eosinophilic Esophagitis: Outcomes From AGREE

AGREE [A Working Group on PPI-REE) was convened to update the previously published guidelines on diagnostic criteria for eosinophilic esophagitis.

Postpartum Pain Management Recommendations From the American College of Obstetricians and Gynecologists

Postpartum Pain Management Recommendations From the American College of Obstetricians and Gynecologists

A committee from the American College of Obstetricians and Gynecologists formulated several recommendations for safely managing pain and fatigue in women during the early postpartum period.

Inactivated Influenza Vaccine Preferred for Nursing Mothers

Inactivated Influenza Vaccine Preferred for Nursing Mothers

Women receiving the inactivated influenza vaccine demonstrated superior antibody response compared with those receiving the live attenuated influenza vaccine.

Successful Screening and Referral for HIV, Hepatitis C in a Trauma Population

Successful Screening and Referral for HIV, Hepatitis C in a Trauma Population

Investigators added hepatitis C virus and HIV screening tests to standard trauma activation laboratory orders.

Should You Record Your Patient Encounters? An Interview With Dr James Ryan

Should You Record Your Patient Encounters? An Interview With Dr James Ryan

Patients are increasingly recording physician visits on their phones, should physicians do the same. MPR spoke with physician who advocates for recording in clinical practice.

Collagen Degradation, Formation Elevated in Patients With Exacerbated COPD

Collagen Degradation, Formation Elevated in Patients With Exacerbated COPD

Serologically assessed collagen remodeling plays a key role in the severity of COPD, as determined by airflow limitation and dyspnea, as well as in disease outcomes.

L-Glutamine Oral Therapy Reduces Sickle Cell-Related Pain Better Than Placebo

L-Glutamine Oral Therapy Reduces Sickle Cell-Related Pain Better Than Placebo

L-Glutamine oral treatment with or without hydroxyurea reduces pain crises better than placebo in individuals with sickle cell disease.

HPV Vaccine Failure Rates May Be Higher in Women, Girls With HIV

HPV Vaccine Failure Rates May Be Higher in Women, Girls With HIV

Vaccinated women and girls living with HIV may be at greater risk for HPV vaccine failure compared with women and girls without HIV.

Coordinated Care Enhances Access to Hepatitis C Antiviral Treatment

Coordinated Care Enhances Access to Hepatitis C Antiviral Treatment

Coordinated treatment programs may improve treatment outcomes in patients with hepatitis C infection.

Wellness Vacations Prioritize a Healthy Lifestyle During Travel

Wellness Vacations Prioritize a Healthy Lifestyle During Travel

Wellness travel comes in many forms: from coastal bike rides to weeklong workout programs with celebrity trainers.

New Clinical Guideline for Evaluating Alzheimer's, Related Dementias

New Clinical Guideline for Evaluating Alzheimer's, Related Dementias

Currently, there are no US consensus on best clinical practice guidelines that incorporate multispecialty recommendations for evaluating cognitive impairment that are thought to be due to Alzheimer's disease and Related Dementias (ADRD) for use by physicians and nurse practitioners.

Lithium Use During Pregnancy Linked to Infant, Maternal Health Risks

Lithium Use During Pregnancy Linked to Infant, Maternal Health Risks

Maternal lithium use in the first trimester of pregnancy may increase the risk for infant malformations.

Increased Maternal Mortality Risk Associated With Recurrent Preeclampsia

Increased Maternal Mortality Risk Associated With Recurrent Preeclampsia

Recurrent hypertensive disease of pregnancy is associated with increased risk for early all-cause and some cause-specific mortality.

Clinicians Warn That Zika Virus May Still Be an Area of Concern for Travelers

Clinicians Warn That Zika Virus May Still Be an Area of Concern for Travelers

Infectious disease experts from Emory University School of Medicine recommend that patients contemplating travel to Zika-affected areas consult with their care providers regarding travel plans and potential Zika virus testing.

NP, PA Treatment Comparable for Patients With CVD or Diabetes

NP, PA Treatment Comparable for Patients With CVD or Diabetes

Effectiveness of care and healthcare resource use for diabetes or cardiovascular disease were comparable among patients receiving care from an NP vs those managed by a PA.

New Poll Offers Women's Perspective on Women's Health Issues

New Poll Offers Women's Perspective on Women's Health Issues

The Kaiser Family Foundation recently released results from a new poll examining the public's view on women's issues.

Congenital Anomalies Not Linked to Metformin Use After First Trimester

Congenital Anomalies Not Linked to Metformin Use After First Trimester

Metformin use during the first trimester of pregnancy is not correlated with an increased risk of congenital anomalies.

Interrelationship Between Celiac Disease, Self-Reported Wheat Sensitivity, and Functional GI Disorders

Interrelationship Between Celiac Disease, Self-Reported Wheat Sensitivity, and Functional GI Disorders

Individuals with clinically diagnosed celiac disease are at greater risk for chronic gastrointestinal symptoms, possibly fitting modified Rome criteria for irritable bowel syndrome and functional dyspepsia.

Fidaxomicin Effective for Long-Term Cure of Clostridium difficile

Fidaxomicin Effective for Long-Term Cure of Clostridium difficile

Fidaxomicin demonstrated the strongest evidence for being the most effective treatment in providing a long-term cure for C difficile infection.

Cardiac Pathology in SUDEP Compared With Sudden Arrhythmic or Traumatic Deaths

Cardiac Pathology in SUDEP Compared With Sudden Arrhythmic or Traumatic Deaths

Causes of death in patients with epilepsy were assessed to determine the presence of cardiac pathology.

Skin Cancer Education May Improve Sun Protection Practices Among Organ Transplant Recipients

Skin Cancer Education May Improve Sun Protection Practices Among Organ Transplant Recipients

The use of multiple sun protection measures was defined as the use of 2 or more of these measures more than 50% of the time when the individual was outdoors.

Lack of Vaccination in High-Exempt Areas Linked to Medical Distrust

Lack of Vaccination in High-Exempt Areas Linked to Medical Distrust

Exemption from vaccination is common in Arizona school districts due to lack of trust in medical establishments.

Food-Induced Anaphylaxis Risk in Infants, Children

Food-Induced Anaphylaxis Risk in Infants, Children

Respiratory symptoms were more common in older children compared with infants who presented with food-induced anaphylaxis.

Preeclampsia With Severe Features Increases Risk for Cardiac Abnormalities

Preeclampsia With Severe Features Increases Risk for Cardiac Abnormalities

Women with preeclampsia with severe features had increased right ventricular systolic pressure and decreased global right ventricular longitudinal systolic strain.

Link Between Bullous Pemphigoid and Dipeptidyl Peptidase-4 Inhibitors

Link Between Bullous Pemphigoid and Dipeptidyl Peptidase-4 Inhibitors

The relationship between bullous pemphigoid and dipeptidyl peptidase-4 inhibitors in type 2 diabetes.

Single High-Dose Liposomal Amphotericin B Effectively Treats HIV-Associated Cryptococcal Meningitis

Single High-Dose Liposomal Amphotericin B Effectively Treats HIV-Associated Cryptococcal Meningitis

Single high-dose liposomal amphotericin B (L-AmB) is non-inferior to daily dosed L-AmB at the standard dose in treatment of fungal clearance in HIV-associated cryptococcal meningitis.

Therapy Focusing on Mindfulness, Interoception Improves Outcomes for Women With Substance Use Disorder

Therapy Focusing on Mindfulness, Interoception Improves Outcomes for Women With Substance Use Disorder

These findings are consistent with emerging neurocognitive models linking interoception to emotion regulation and related health outcomes, providing valuable input in improving substance use disorder treatment.

Guidelines for Management of Hypothalamic-Pituitary, Growth Disorders in Childhood Cancer Survivors

Guidelines for Management of Hypothalamic-Pituitary, Growth Disorders in Childhood Cancer Survivors

The Endocrine Society, European Society of Endocrinology, and Pediatric Endocrine Society issue guidelines for the management of hypothalamic-pituitary and growth disorders in childhood cancer survivors.

Chemotherapy With Bevacizumab May Improve Some Ovarian Cancer Outcomes, Worsen Others

Chemotherapy With Bevacizumab May Improve Some Ovarian Cancer Outcomes, Worsen Others

First-line chemotherapy in combination with bevacizumab, compared with chemotherapy alone, may benefit patients with ovarian cancer and elevated neutrophil-to-lymphocyte ratios.

Emergency Physicians Offer Recommendations for Identifying and Managing Opioid Use Disorder

Emergency Physicians Offer Recommendations for Identifying and Managing Opioid Use Disorder

American emergency medicine physicians have been taking measures to address the ongoing opioid crisis, which affects emergency departments throughout the country.

Radiofrequency Denervation Efficacious in Treating Thoracic Zygapophyseal Joint Pain

Radiofrequency Denervation Efficacious in Treating Thoracic Zygapophyseal Joint Pain

Radiofrequency denervation, typically used to treat lumbar and cervical zygapophyseal joint pain, has shown efficacy in treating thoracic zygapophyseal joint pain.

Is New Surveillance Monitoring Required for Enterococcal Oxazolidinone Resistance?

Is New Surveillance Monitoring Required for Enterococcal Oxazolidinone Resistance?

A study was conducted to evaluate the oxazolidinone resistance mechanisms of enterococci bacteria.

Progress Report in Cancer Control: How Are We Doing?

Progress Report in Cancer Control: How Are We Doing?

An analysis of population data on cancer incidence, survival, and mortality revealed that early interventions and improvements to treatments contributed to a 26% decline in cancer deaths from 1991 to 2015.

No Difference in CEA vs CA125/CEA Ratio for Identifying Ovarian Masses

No Difference in CEA vs CA125/CEA Ratio for Identifying Ovarian Masses

No significant difference was identified in combination CA125/CEA ratio vs CEA alone in distinguishing ovarian neoplasms from ovarian metastases.

Avastin Plus ChemoTx Approved for Advanced Ovarian Cancer After Resection

Avastin Plus ChemoTx Approved for Advanced Ovarian Cancer After Resection

Study patients who received Avastin plus chemotherapy followed by Avastin alone, had a greater median PFS vs patients who received chemotherapy alone (18.2 months vs 12 months; hazard ratio [HR] 0.62, 95% CI, 0.52-0.75; P<.0001).

Overuse of Neuroimaging in the Emergency Department Reported for Pediatric Headache

Overuse of Neuroimaging in the Emergency Department Reported for Pediatric Headache

Investigators examined rates, predictors, and outcomes of neuroimaging in pediatric and adolescent patients who presented to the ED with a headache.

Differences Between Cyclothymic Disorder and Unspecified Bipolar Disorder in Youth May Indicate Course of Disorder

Differences Between Cyclothymic Disorder and Unspecified Bipolar Disorder in Youth May Indicate Course of Disorder

Investigators sought to determine the differences between youth with cyclothymic disorder and bipolar disorder not otherwise specified.

Pain Societies Issue Guidelines on Use of Ketamine for the Management of Acute Pain

Pain Societies Issue Guidelines on Use of Ketamine for the Management of Acute Pain

Consensus guidelines regarding the use of ketamine for the management of acute pain have been approved.

Acute Coronary Syndrome Risk Elevated in Siblings of Patients With RA

Acute Coronary Syndrome Risk Elevated in Siblings of Patients With RA

Siblings of patients with rheumatoid arthritis appear to have an increased risk for acute coronary syndrome, which suggests there is a shared susceptibility between the 2 conditions.

Otitis Media-Related Ambulatory Visits Declined After Pneumococcal Conjugate Vaccine

Otitis Media-Related Ambulatory Visits Declined After Pneumococcal Conjugate Vaccine

The administration of PCV7 and PCV13 reduced the number of ambulatory visits for otitis media in pediatric patients.

Menopause Transition Often Prompts Changes in Migraine Pattern, Characteristics

Menopause Transition Often Prompts Changes in Migraine Pattern, Characteristics

This retrospective study sought to assess migraine patterns in 69 menopausal women between ages 40 and 60 who were treated at Partners Healthcare Hospitals for concurrent migraine headache.

fMRI Evidence for Social Motivation Hypothesis of Autism

fMRI Evidence for Social Motivation Hypothesis of Autism

These data show that ASD may arise from an early neurobiological difference in response to rewarding social stimuli, which could result in reduced social motivation.

Retinal Nerve Fiber Layer Thickness May Be Associated With Cognitive Function

Retinal Nerve Fiber Layer Thickness May Be Associated With Cognitive Function

Thinning of the retinal nerve fiber layer has been linked to worsening cognitive function and may be valuable in identifying individuals who may be at risk for cognitive decline.

Blister Packs for Several Meds Recalled Due to Risk of Harm to Children

Blister Packs for Several Meds Recalled Due to Risk of Harm to Children

The recall affects approximately 470,000 units that include drugs packaged with 3 to 10 tablets per blister card. The blister packs were developed for use in hospitals, however some were sent to retail pharmacies and were likely dispensed for in-home use.

FDA Takes Steps to Reconcile Needs of Patients With Chronic Pain, Efforts to Curb Opioid Epidemic

FDA Takes Steps to Reconcile Needs of Patients With Chronic Pain, Efforts to Curb Opioid Epidemic

A panel discussion event held at the US Food and Drug Administration gathered patients with chronic pain and FDA officials, to reconcile concerns around prescriptions of opioid medications with the needs of these patient populations.

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