Web Exclusives

Low-fat vs low-carbohydrate diets for weight loss

Low-fat vs low-carbohydrate diets for weight loss

Is there a significant difference between low-fat and low-carbohydrate diets on weight loss?

Cesarean delivery linked to long-term pregnancy complications

Cesarean delivery linked to long-term pregnancy complications

Cesarean delivery is associated with a reduced rate of urinary incontinence and pelvic organ prolapse, but this should be weighed against the association with increased risks for fertility, future pregnancy, and long-term childhood outcome.

HbA1C levels linked to cognitive decline in diabetes

HbA1C levels linked to cognitive decline in diabetes

HbA1C, diabetes status, and cognitive decline during a span of 10 years were compared using data from the English Longitudinal Study of Ageing.

Opioid use increases risk of invasive pneumococcal disease

Opioid use increases risk of invasive pneumococcal disease

The risk of invasive pneumococcal disease is correlated with the prescription opioid use.

Hepatitis B infection prevention: ACIP updated recommendations

Hepatitis B infection prevention: ACIP updated recommendations

The Work Group who authored the new recommendations was made up of professionals from academic medicine, federal and state public health agencies, and medical societies.

Alcohol use disorder: a clinical practice guideline

Alcohol use disorder: a clinical practice guideline

The new guideline focuses on evidence-based treatments in alcohol use disorder such as pharmacologic treatments, naltrexone, disulfiram, and topiramate.

Cerebral palsy, epilepsy risk associated with lower Apgar score

Cerebral palsy, epilepsy risk associated with lower Apgar score

An inverse relation was observed between epilepsy and cerebral palsy and 5-minute and 10-minute Apgar scores.

CDC: Influenza vaccine 25% effective against H3N2 in 2017-2018

CDC: Influenza vaccine 25% effective against H3N2 in 2017-2018

The 2017 to 2018 influenza vaccine reduces the chance of getting the disease by about 33%, but is only 25% effective against H3N2, otherwise known as influenza A.

Pain sensation may be altered by verum, sham electroacupuncture

Pain sensation may be altered by verum, sham electroacupuncture

Functional magnetic resonance imaging was used to monitor brain activity in patients with osteoarthritis who were administered either genuine or placebo electroacupuncture.

Ovarian cancer risk reduced with oral contraceptives

Ovarian cancer risk reduced with oral contraceptives

The use of oral contraceptives did not reduce the risks of breast cancer or colorectal cancer.

Ovarian cancer screening: updated recommendations from the USPSTF

Ovarian cancer screening: updated recommendations from the USPSTF

The USPSTF has issued an updated recommendation statement on ovarian cancer screening.

Primary gastrinomas of the hepatobiliary tract may occur in patients with Zollinger-Ellison syndrome

Primary gastrinomas of the hepatobiliary tract may occur in patients with Zollinger-Ellison syndrome

Lymph nodes proximal to hepatic or biliary gastrinomas will likely require extraction as many in the surround region will have metastasized.

Assessing impacts of antidepressants on ovarian cancer risk

Assessing impacts of antidepressants on ovarian cancer risk

Past epidemiological investigations resulted in inconsistent reports on the affiliation between antidepressants and the risk of ovarian cancer.

ACIP releases 2018 recommended immunization schedule for adults

ACIP releases 2018 recommended immunization schedule for adults

The Advisory Committee on Immunization Practices updated its immunization recommendations for adults.

Patent foramen ovale associated with stroke risk after noncardiac surgery

Patent foramen ovale associated with stroke risk after noncardiac surgery

Patients diagnosed with PFO prior to noncardiac surgery have an elevated ischemic stroke risk.

Standards of Medical Care in Diabetes modified for cardiovascular disease

Standards of Medical Care in Diabetes modified for cardiovascular disease

The ADA's updates include a modified patient-focused care algorithm as well as improved risk management for CVD.

Gestational diabetes increases T2D, hypertension, heart disease risk

Gestational diabetes increases T2D, hypertension, heart disease risk

Women with gestational diabetes have a greater risk of developing T2D and cardiovascular events than women who were not previously diagnosed with the disease.

Long-term memory enhanced by electrical stimulation of the amygdala

Long-term memory enhanced by electrical stimulation of the amygdala

Modulate electrical stimulation of the amygdala may improve declarative memory without provoking any emotional reaction.

2018 Immunization schedule for children, adolescents: ACIP recommendations

2018 Immunization schedule for children, adolescents: ACIP recommendations

The updates contain new or revised ACIP recommendations for poliovirus, influenza, and measles, mumps, and rubella vaccines, as well as a clarification of the recommendations for rotavirus and pneumococcal vaccines.

NFL players do not have significantly increased mortality risk

NFL players do not have significantly increased mortality risk

Among NFL football players who began their careers between 1982 and 1992, career participation in the NFL, compared with limited NFL exposure obtained primarily as an NFL replacement player during a league-wide strike, was not associated with a statistically significant difference in long-term all-cause mortality.

Pediatric obesity rate may decrease with special nutrition programs

Pediatric obesity rate may decrease with special nutrition programs

Severe obesity may decline in children enrolled in specialized diet programs.

High fitness level associated with lower waist circumference, independent of BMI

High fitness level associated with lower waist circumference, independent of BMI

The investigators studied the association between abdominal fat, inflammation, and fitness by measuring body weight, dimensions, and blood samples.

HCV treatment hinders liver fibrosis progression

HCV treatment hinders liver fibrosis progression

Patients with chronic HCV with a sustained virologic response were more likely to have a reduced progression of liver fibrosis.

Predicting mortality and outcomes after a subarachnoid hemorrhage

Predicting mortality and outcomes after a subarachnoid hemorrhage

A clinical prediction tool successfully forecasts subarachnoid hemorrhage management from ruptured intracranial aneurysms.

Takeout meal consumption linked to adverse health risks in children

Takeout meal consumption linked to adverse health risks in children

The increased rate of takeout meal consumption was correlated with higher total fat intake and lower intake of vitamin C, iron, and calcium.

Delayed treatment after epileptic seizure onset leads to higher mortality rate

Delayed treatment after epileptic seizure onset leads to higher mortality rate

Ill-timed administration of benzodiazepine treatment in pediatric patients with refractory convulsive status epilepticus is associated with many short-term adverse events.

ACA has led to reduced cost burden for lowest to middle income households

ACA has led to reduced cost burden for lowest to middle income households

The Affordable Care Act is associated with moderate reductions in the cost burden for the lowest-, low-, and middle-income households.

Depressive symptoms may increase mortality risk in patients undergoing aortic valve replacement

Depressive symptoms may increase mortality risk in patients undergoing aortic valve replacement

In patients undergoing TAVR or SAVR, approximately 1 in 3 had depressive symptoms at baseline and a higher risk of short-term and midterm mortality.

Anxiety symptoms linked to episodic memory reduction in older adults

Anxiety symptoms linked to episodic memory reduction in older adults

A significant affiliation between symptoms of anxiety and a decrease in episodic memory was reported in healthy seniors 60 years and older.

E-cigarettes may lead youth to start smoking, adults to stop: NASEM report

E-cigarettes may lead youth to start smoking, adults to stop: NASEM report

A congressionally mandated report has found that e-cigarettes are likely to be far less harmful than conventional cigarettes, although they are not without health risks.

Acute ischemic stroke: new guidelines open treatment window to 24 hours

Acute ischemic stroke: new guidelines open treatment window to 24 hours

At the 2018 International Stroke Conference in Los Angeles, the AHA/ASA released updated guidelines for the early management of ischemic strokes, which account for 87% of all strokes.

Airborne influenza transmission possible through exhalation

Airborne influenza transmission possible through exhalation

Influenza infections are independently compartmentalized in the upper and lower airways.

Low caffeine level may be biomarker for Parkinson disease

Low caffeine level may be biomarker for Parkinson disease

Caffeine and its 3 downstream metabolites may be helpful as a biomarker for Parkinson disease.

Postoperational opioid misuse linked to prescription longevity

Postoperational opioid misuse linked to prescription longevity

Duration, more than dosage, may increase the risk of misuse in opioid naïve patients.

Glucocorticoid treatment ineffective for reducing sepsis-related mortality

Glucocorticoid treatment ineffective for reducing sepsis-related mortality

Hydrocortisone treatment does not effectively reduce mortality in sepsis.

Herpes zoster subunit vaccine more effective, less expensive than live attenuated herpes zoster vaccine

Herpes zoster subunit vaccine more effective, less expensive than live attenuated herpes zoster vaccine

The adjuvanted herpes zoster subunit vaccine is more effective and less expensive than the live attenuated herpes zoster vaccine at all ages.

Clinical tool may help in prostate cancer screenings

Clinical tool may help in prostate cancer screenings

Polygenic hazard scores were developed to help predict the age of onset of prostate cancer.

Congress urged to reverse CMS clinician payment policy

Congress urged to reverse CMS clinician payment policy

Healthcare organizations are calling on Congress to reverse the new CMS policy that has the potential to jeopardize patient access to Part B drug therapies.

Should a "do not resuscitate" tattoo on an unconscious patient be honored?

Should a "do not resuscitate" tattoo on an unconscious patient be honored?

A patient presented with COPD, diabetes, and atrial fibrillation and was found to have a large tattoo across his chest reading, "DO NOT RESUSCITATE," followed by his signature.

Novel device may ease symptoms of tinnitus

Novel device may ease symptoms of tinnitus

Bimodal auditory-somatosensory treatment is noninvasive and showed no side effects.

Gastric bypass vs sleeve gastrectomy in morbidly obese patients

Gastric bypass vs sleeve gastrectomy in morbidly obese patients

There is no statistically significant difference in weight loss at 5 years after laparoscopic sleeve gastrectomy vs laparoscopic Roux-en-Y gastric bypass in morbidly obese patients.

Adolescent idiopathic scoliosis screening: a USPSTF recommendation statement

Adolescent idiopathic scoliosis screening: a USPSTF recommendation statement

The USPSTF has updated its recommendations on screening for idiopathic scoliosis in asymptomatic adolescents.

New long-acting bronchodilator use linked to CV risk in COPD patients

New long-acting bronchodilator use linked to CV risk in COPD patients

Use of long-acting bronchodilators is linked to cardiovascular risks in patients with COPD.

Dementia risk linked to apathy, depression in older adults

Dementia risk linked to apathy, depression in older adults

Apathy and depressive symptoms are independently associated with incident dementia in community-dwelling older people.

7 online tools and mobile apps recommended to reduce burnout, stress

7 online tools and mobile apps recommended to reduce burnout, stress

Researchers recommend 7 online tools and mobile apps to help healthcare professionals reduce stress, burnout, depression, and suicidal behaviors.

Maternal folic acid, multivitamin use linked to reduced autism risk

Maternal folic acid, multivitamin use linked to reduced autism risk

Use of folic acid or multivitamins during pregnancy is associated with a significantly reduced risk of ASD in offspring.

Ibuprofen use may compromise reproductive health in men

Ibuprofen use may compromise reproductive health in men

Increased ibuprofen administration elevates LH and decreases testosterone to LH and inhibin B to FSH ratios in young adult men.

FDA approves shock wave device to treat diabetic foot ulcers

FDA approves shock wave device to treat diabetic foot ulcers

The FDA has approved the Dermapace System for treatment of chronic, full-thickness diabetic foot ulcers.

Mechanically expanded TAVR may benefit high-risk aortic stenosis patients

Mechanically expanded TAVR may benefit high-risk aortic stenosis patients

MEV aortic valve replacement is noninferior to SEV aortic valve replacement in high-risk patients with aortic stenosis.

CDC investigating E. coli outbreak in 13 states

CDC investigating E. coli outbreak in 13 states

An outbreak of E. coli O157:H7 have been reported in 13 states in the US as well as Canada.

Addition of new class of antihypertensive drug effective for lowering BP

Addition of new class of antihypertensive drug effective for lowering BP

Addition of a new class of antihypertensive drugs to existing treatment greatly decreases SBP in previously medicated patients with HT.

Positive attitude linked to lower mortality risk after cardiovascular event

Positive attitude linked to lower mortality risk after cardiovascular event

Positive emotions and low levels of depression after a cardiovascular disease (CVD) event are associated with low risk for mortality during a 15-year period.

Air pollution increases mortality risk in older adults

Air pollution increases mortality risk in older adults

Exposure to surrounding air pollutants and warm season ozone are linked to increased risk of death.

Mild cognitive impairment: a practice guideline update

Mild cognitive impairment: a practice guideline update

The American Academy of Neurology has released updated guideline recommendations for mild cognitive impairment.

Pet ownership not linked to aging biomarkers in the elderly

Pet ownership not linked to aging biomarkers in the elderly

Pet ownership is not linked to decreased aging in the elderly.

CDC receives list of banned terms for 2018

CDC receives list of banned terms for 2018

Policy analysts at the CDC and another, as yet unnamed Department of Health and Human Services agency, have been informed to stop using certain terms in documents to be used in next year's budget.

Green leafy vegetable consumption linked to slower cognitive decline

Green leafy vegetable consumption linked to slower cognitive decline

Intake of primary nutrients and bioactives in green leafy vegetables is associated with slower cognitive decline.

FDA proposes new enforcement approach for homeopathic drugs

FDA proposes new enforcement approach for homeopathic drugs

The FDA is proposing a new, risk-based enforcement approach to homeopathic drug products that have the greatest potential to harm patients.

Vitamin D, calcium supplements do not reduce fracture risk in older adults

Vitamin D, calcium supplements do not reduce fracture risk in older adults

Findings do not support routine vitamin D and calcium supplementation in community-dwelling older adults for lowering the incidence of osteoporosis-related fractures.

Higher education may help reduce Alzheimer's disease risk

Higher education may help reduce Alzheimer's disease risk

Attaining higher education may aid in the prevention of Alzheimer's disease.

Man flu: man-made or real illness?

Man flu: man-made or real illness?

Men may experience a lower immune response than women, adding insight to the man flu debate.

Steady rate of marijuana use associated with decline in cigarette, alcohol use in adolescents

Steady rate of marijuana use associated with decline in cigarette, alcohol use in adolescents

Adolescent marijuana prevalence today would be at or near record highs if cigarette use had not declined since 2005.

AAFP does not endorse new hypertension guideline

AAFP does not endorse new hypertension guideline

The AAFP continues to use the 2014 JNC8 guideline instead of the 2017 AHA/ACC update.

Hormonal contraception use linked to an increased risk of breast cancer

Hormonal contraception use linked to an increased risk of breast cancer

Breast cancer diagnosis is higher among women who currently use or recently used contemporary hormonal contraceptives than among women who have never used hormonal contraceptives.

Average birth weights have decreased among infants born in Flint, Michigan

Average birth weights have decreased among infants born in Flint, Michigan

Average birth weights among infants born in Flint, Michigan, have decreased after the city's shift from using the Detroit Water Authority to the Flint River for its tap water source.

BMI may not indicate obesity in postmenopausal women

BMI may not indicate obesity in postmenopausal women

Body mass index BMI at a cut-point of 30 kg/m2 may not be an appropriate indicator of obesity in postmenopausal women.

Blood pressure decreases more than a decade before death

Blood pressure decreases more than a decade before death

Blood pressure decreases more than a decade before death in patients older than 60 years.

VTE risk linked to increased television watching

VTE risk linked to increased television watching

Increased frequency of television viewing may be linked to an increased risk for venous thromboembolism.

Menopausal hormone therapy for chronic conditions: USPSTF's final recommendation

Menopausal hormone therapy for chronic conditions: USPSTF's final recommendation

The USPSTF has updated its recommendations on the use of menopausal hormone therapy for the primary prevention of chronic conditions.

Oral capsule of fecal transplant may be effective for C. difficile infection

Oral capsule of fecal transplant may be effective for C. difficile infection

Oral capsule FMT and colonoscopy delivery showed similar patient outcomes, low rate differences, and high success rates.

Combination ART may prevent progressive brain injury in HIV patients

Combination ART may prevent progressive brain injury in HIV patients

Post-seroconversion brain morphology can occur in HIV patients, but aviremia maintenance via cART can slow of prevent brain injuries.

HIV infection to diagnosis time decreasing

HIV infection to diagnosis time decreasing

A new report from the CDC finds that HIV is being diagnosed sooner after initial infection than in previous years.

Solutions needed for increasing physician burnout rate in the US

Solutions needed for increasing physician burnout rate in the US

Although awareness of physician burnout has increased, the problem continues to affect medical students, residents, and practicing physicians.

Prescription video game shows promising results for pediatric ADHD

Prescription video game shows promising results for pediatric ADHD

A study of an investigational digital medicine achieves its primary efficacy end point in pediatric ADHD.

Omega-3 supplementation improves pediatric executive functioning

Omega-3 supplementation improves pediatric executive functioning

Omega-3 supplementation in children with mood disorders is associated with decreased impairment in executive functioning.

Body mass index and dementia risk: Is there a connection?

Body mass index and dementia risk: Is there a connection?

Higher BMI is associated with increased dementia risk when weight was measured more than 20 years before dementia diagnosis, but this association is reversed when BMI was assessed less than 10 years before dementia diagnosis.

Sexual harassment: How far have we come?

Sexual harassment: How far have we come?

Researchers sought to determine how much has changed since the Journal of Occupational Health Psychology first reported on sexual harassment two decades ago.

DOACs vs warfarin for stroke prevention in atrial fibrillation

DOACs vs warfarin for stroke prevention in atrial fibrillation

Many direct acting oral anticoagulants may be more beneficial than warfarin.

AHA outlines concerns against the Senate tax reform bill

AHA outlines concerns against the Senate tax reform bill

The American Heart Association has released a statement detailing their concerns about the tax reform bill.

FDA approves weekly diabetes drug that may also be beneficial for weight loss

FDA approves weekly diabetes drug that may also be beneficial for weight loss

The FDA has approved semaglutide injection as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.

Methotrexate vs tumor necrosis factor inhibitors for pediatric psoriasis

Methotrexate vs tumor necrosis factor inhibitors for pediatric psoriasis

Medication-related adverse events occur more frequently with methotrexate in children with moderate to severe psoriasis.

ADHD medication in pregnancy linked to few absolute increased risks

ADHD medication in pregnancy linked to few absolute increased risks

Women with significant attention-deficit/hyperactivity disorder do not need to stop treatment during pregnancy.

Oral insulin does not prevent type 1 diabetes in relatives of patients

Oral insulin does not prevent type 1 diabetes in relatives of patients

Oral insulin usage does not prevent the development of type 1 diabetes in relatives of patients.

Residual anxiety after venlafaxine treatment associated with depressive relapse

Residual anxiety after venlafaxine treatment associated with depressive relapse

Venlafaxine was superior to lithium in reducing symptoms of both bipolar II, depression, and anxiety.

Adolescent acne not linked to malignant melanoma in men

Adolescent acne not linked to malignant melanoma in men

Body mass index is linked to malignant melanoma in men.

Healthcare system fires 50 employees for refusing influenza vaccination

Healthcare system fires 50 employees for refusing influenza vaccination

A Minnesota-based hospital chain fires about 50 employees for refusal to receive the influenza vaccine.

Drinking 3 to 4 cups of coffee per day linked to potential health benefits

Drinking 3 to 4 cups of coffee per day linked to potential health benefits

Meta-analyses suggest that drinking 3-4 cups of coffee a day has more associated health benefits than risks.

Low-dose aspirin ineffective for venous leg ulcers

Low-dose aspirin ineffective for venous leg ulcers

Low-dose aspirin does not decrease healing time for patients with venous leg ulcers.

FDA approves Heplisav-B vaccine for hepatitis B treatment

FDA approves Heplisav-B vaccine for hepatitis B treatment

The Food and Drug Administration (FDA) has approved Heplisav-B for the prevention of infection caused by all known subtypes of hepatitis B virus.

Endovascular strategy more effective than open repair for ruptured abdominal aortic aneurysms

Endovascular strategy more effective than open repair for ruptured abdominal aortic aneurysms

Treating patients with ruptured abdominal aortic aneurysms with endovascular strategy over open repair may increase survival and decrease cost.

Reduced effectiveness of last season's flu vaccine traced to mutation in chicken eggs

Reduced effectiveness of last season's flu vaccine traced to mutation in chicken eggs

New virus mutations make antibody binding difficult as mismatches in vaccines and viruses emerge.

FDA warns that febuxostat may increase risk of heart-related mortality

FDA warns that febuxostat may increase risk of heart-related mortality

Preliminary clinical trial results show more heart-related deaths occur in patients taking febuxostat compared to allopurinol.

Brief intervention may be beneficial for adolescents with chronic pain

Brief intervention may be beneficial for adolescents with chronic pain

A combination of psychoeducation, cognitive-based therapy, visualization, and breathing exercises may represent a tolerable and readily accepted complementary therapeutic approach for adolescent patients with chronic pain.

ASCO: Alcohol consumption increases cancer risk

ASCO: Alcohol consumption increases cancer risk

According to a special report by the American Society of Clinical Oncology, alcohol consumption is a definite risk for cancer development.

FDA tips for holiday food health, safety

FDA tips for holiday food health, safety

The FDA has published recommendations to prevent foodborne illnesses during the holiday season.

Low-fat diets may reduce all-cause mortality risk in obese patients

Low-fat diets may reduce all-cause mortality risk in obese patients

Weight-loss diets low in fat and saturated fat consumption, with or without added exercise, may reduce the risk for all-cause mortality in obese adults.

Dual HIV treatment provides simple, safe salvage regimen

Dual HIV treatment provides simple, safe salvage regimen

The dual combination of dolutegravir plus darunavir/ritonavir provided a simple and safe salvage therapy to suppress viral replication without metabolic impact in patients infected with HIV-1.

USPSTF recommends osteoporosis screening, testing in women aged 65 and older

USPSTF recommends osteoporosis screening, testing in women aged 65 and older

The USPSTF has updated its recommendations on osteoporosis screening and testing in women and men.

FDA approves schizophrenia digital ingestion sensor

FDA approves schizophrenia digital ingestion sensor

The US Food and Drug Administration has approved Abilify MyCite, which contains an ingestible sensor that records whether or not the medication was taken.

Hepatitis increases mortality rates in HIV patients

Hepatitis increases mortality rates in HIV patients

Hepatitis B and hepatitis C may increase mortality risks in HIV patients.

Sign Up for Free e-newsletters